毒虫威

  • 基本信息
  • 物化性质
  • 安全信息
  • 毒理性
  • MSDS
  • 结构与计算化学
  • 上游产品
  • 表征图谱

毒虫威 基本信息

中文名称:
毒虫威 
中文别名:
毒虫畏;
代草克;
2-氯-1-(2,4-二氯苯基)乙烯基二乙基磷酸酯;
GC-4072 
英文名称:
chlorfenvinfos
英文别名:
chlorfenvinfos;
Chlorfenvinphos;
(1Ξ)-2-chloro-1-(2,4-dichlorophenyl)ethenyl diethyl phosphate;
chlorfenvinphos;
clofenvinfos;
(EZ)-2-chloro-1-(2,4-dichlorophenyl)vinyl diethyl phosphate;
Chlorfenvinfos;
2-chloro-1-(2,4-dichlorophenyl)ethenyl diethyl phosphate 
CAS No.:
470-90-6
分 子 式:
C12H14Cl3O4P
分 子 量:
359.57000
精确分子量:
357.97000
PSA:
54.57000
MDL:
MFCD00041818
EINECS:
207-432-0
BRN:
8712900
InChI:
The Key: FSAVDKDHPDSCTO-WQLSENKSSA-N
风险术语:
24-28-50/53
分子结构式:
SDS:
查看

毒虫威 物化性质

外观与性状:
琥珀色的液体,带有一种温和化学气味
密度:
1.373g/cm3
熔点:
-23 to -19ºC
沸点:
396.5ºC at 760 mmHg
闪点:
100 °C
水溶解性:
Insoluble
折射率:
1.534
蒸汽压:
3.9E-06mmHg at 25°C
存储条件/存储方法:
库房通风低温干燥,与食品原料分开储运
稳定性相关:

明火可燃; 受热放出有毒氧化磷、氯化物气体

毒虫威 安全信息

包装等级:
II
风险类别:
6.1(a)
海关代码:
2919900034
危险类别码:
R24;R28;R50/53
安全说明:
S28-S36/37-S45-S60-S61-S62
RTECS号:
TB8750000
安全标志:
S28:接触皮肤之后,立即使用大量皂液洗涤。
S45:出现意外或者感到不适,立刻到医生那里寻求帮助(最好带去产品容器标签)。
S60:本物质残余物和容器必须作为危险废物处理。
S61:避免排放到环境中。参考专门的说明/安全数据表。
:
危险标志:
T+;N

毒虫威 毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TB8750000
CHEMICAL NAME :
Phosphoric acid, 2-chloro-1-(2,4-dichlorophenyl)vinyl diethyl ester
CAS REGISTRY NUMBER :
470-90-6
LAST UPDATED :
199709
DATA ITEMS CITED :
37
MOLECULAR FORMULA :
C12-H14-Cl3-O4-P
MOLECULAR WEIGHT :
359.58
WISWESSER LINE NOTATION :
GR CG DYU1GOPO&O2&O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Human
DOSE/DURATION :
10 mg/kg
TOXIC EFFECTS :
Blood - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
10 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
50 mg/m3/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
26400 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
8500 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
7 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
6600 ug/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Gastrointestinal - changes in structure or function of salivary glands Gastrointestinal - hypermotility, diarrhea
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
65 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
336 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
87 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
339 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
87 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
1200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
51 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Gastrointestinal - changes in structure or function of salivary glands Gastrointestinal - hypermotility, diarrhea
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Gastrointestinal - changes in structure or function of salivary glands Gastrointestinal - hypermotility, diarrhea
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Gastrointestinal - changes in structure or function of salivary glands Gastrointestinal - hypermotility, diarrhea
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
125 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - pigeon
DOSE/DURATION :
13300 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - chicken
DOSE/DURATION :
29100 ug/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Bird - chicken
DOSE/DURATION :
23100 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - quail
DOSE/DURATION :
148 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - fasciculations Gastrointestinal - hypermotility, diarrhea
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - domestic
DOSE/DURATION :
71250 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - cattle
DOSE/DURATION :
20 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
10 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - wild bird species
DOSE/DURATION :
13 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
420 mg/kg/12W-C
TOXIC EFFECTS :
Endocrine - changes in spleen weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
49 mg/kg/35W-I
TOXIC EFFECTS :
Cardiac - other changes Liver - other changes Kidney, Ureter, Bladder - other changes
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
182 mg/kg/26W-I
TOXIC EFFECTS :
Blood - changes in leukocyte (WBC) count
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
50400 mg/kg/28D-I
TOXIC EFFECTS :
Liver - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
14 mg/kg/17W-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other transferases
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
697 mg/kg/7D-C
TOXIC EFFECTS :
Brain and Coverings - other degenerative changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other esterases
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
2100 ug/kg/12W-C
TOXIC EFFECTS :
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
500 ug/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 116,185,1983 *** REVIEWS *** TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 46,1,1973 TOXICOLOGY REVIEW CNDQA8 Cahiers de Nutrition et de Dietetique. (Editions Meteore, 42, rue du Louvre, 75001 Paris, France) V.1- 1966- Volume(issue)/page/year: 10(3),43,1975 TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 63,1,1976 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989
毒理学数据:

口服-大鼠 LD50: 10 毫克/公斤; 口服-小鼠 LD50: 65 毫克/公斤

毒虫威 MSDS

国标编号: 61874
CAS: 470-90-6
中文名称: 毒虫畏
英文名称: Phosphosric Acid;Chlorfenvinphos
别 名: 杀螟威;2-氯-1-(2,4-二氯苯基)乙烯基二乙基磷酸酯
分子式: C12H14Cl3O4P
分子量: 359.58
熔 点: 167~170℃(66.7Pa)
密 度: 1.36
蒸汽压:
溶解性: 微溶于水,但可与丙酮、乙醇、煤油、丙二醇和二甲苯混
稳定性: 本品能被水缓慢水解,对钢、铁、黄铜等有腐蚀作用,但
外观与性状: 本品是(Z)和(E)异构体的混合物,其中大多数是(Z)异构体,为琥珀色油状液体,(Z:E)异构体的标准比例为8.5:
危险标记: 14(有毒品)
用 途: 杀虫剂,在土壤处理时,可防治地老虎、根蝇等

2.对环境的影响: 毒理学资料 急性毒性:LD50117mg/kg(小鼠经口); 20mg/kg(大鼠经口) 3.现场应急监测方法:   4.实验室监测方法: 气相色谱法,参照《分析化学手册》(第四分册,色谱分析),化学工业出版社 气相色谱法(农作物、水果、蔬菜)《农药残留量气相色谱法》国家商检局编 5.环境标准: 欧洲经济共同体法规(1982)食物中最高残留限值 一般农作物:0.1mg/kg;特定农作物:0.05~0.5mg/kg 美国(1981)食物和饲料中容许残留限值 0.005~0.2mg/kg(特定畜产品) 6.应急处理处置方法: 急性中毒时,立即使患者脱离现场,脱去污染衣服,全身污染部位用肥皂水或碱溶液彻底清洗,如系口服者,应立即口服1~2%苏打水,或用0.2~0.5%高锰酸钾溶液洗胃,并服用片剂解磷毒(PAM)或阿托品1~2片。眼部污染可用苏打水或生理盐水冲洗。 漏应急处理:迅速撤离泄漏污染区人员至安全区,严格限制出入。切断火源。穿防毒服。切断泄漏源。小量泄漏用砂土或其它不燃材料吸附或吸收。也可大量水冲洗,洗水稀释后放入废水系统。大量泄漏:构筑围堤或挖坑收容。用泡沫覆盖降低蒸气灾害。用泵转移至槽车或专用收集器内,回收或运至废物处理场所处置。 消防:用水、砂土、二氧化碳灭火器灭火,应注意穿戴可靠的防毒、防护用品,防止人身中毒。

毒虫威 分子结构与计算化学数据

分子结构数据

五、分子性质数据:

1、   摩尔折射率:81.43

2、   摩尔体积(cm3/mol):261.8

3、   等张比容(90.2K):671.2

4、   表面张力(dyne/cm):43.2

5、   介电常数(F/m):

6、   偶极距(D):

7、   极化率(10-24cm3):32.28

毒虫威 表征图谱

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