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卡比咪嗪 基本信息
- 中文名称：
- 卡比咪嗪
- 中文别名：
- 卡匹帕明;
卡比咪嗪
- 英文名称：
- [1,4'-Bipiperidine]-4'-carboxamide,1'-[3-(10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl]-
- 英文别名：
- 1-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]-4-piperidin-1-ylpiperidine-4-carboxamide;
1'-[3-(10,11-dihydro-dibenzo[b,f]azepin-5-yl)-propyl]-octahydro-[1,4']bipyridinyl-4'-carboxylic acid amide;
EINECS 227-700-0;
Carbadipimidine;
Bay b 4343 b;
Carpipramine (INN);
Carpipramine;
Carpipraminum [INN-Latin];
Carpipramina [INN-Spanish]
- CAS No.：
- 5942-95-0
- 分 子 式：
- C28H38N4O
- 分 子 量：
- 0
- 精确分子量：
- 446.30500
- PSA：
- 52.81000
- EINECS：
- 227-700-0
- InChI：
- The Key: NWPJLRSCSQHPJV-UHFFFAOYSA-N
- 分子结构式：
-
- SDS：
- 查看
卡比咪嗪 物化性质
- 密度：
- 1.143g/cm3
- 沸点：
- 637.1ºC at 760 mmHg
- 闪点：
- 339.1ºC
- 折射率：
- 1.598
- 存储条件/存储方法：
- 库房低温通风干燥
卡比咪嗪 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- HO0875000
- CHEMICAL NAME :
- 5H-Dibenz(b,f)azepine,
10,11-dihydro-5-(3-(4-piperidino-4-carbamoylpiperidin
o)propyl)-
- CAS REGISTRY NUMBER :
- 5942-95-0
- BEILSTEIN REFERENCE NO. :
- 0502521
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C28-H38-N4-O
- MOLECULAR WEIGHT :
- 446.70
- WISWESSER LINE NOTATION :
- T C676 BN&T&J B3- AT6NTJ DVZ D- AT6NTJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1025 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,63,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 76 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,63,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 37 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,63,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2180 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,63,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 136 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,38,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 28 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,63,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 18 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,63,1972
