磷酸氢钙(二水)

  • 基本信息
  • 制备方法及用途
  • 物化性质
  • 安全信息
  • 毒理性
  • MSDS
  • 结构与计算化学
  • 上游产品
  • 下游产品
  • 表征图谱

磷酸氢钙(二水) 基本信息

中文名称:
磷酸氢钙(二水) 
中文别名:
磷酸氢钙;
磷酸氢钙二水合物;
二水合磷酸氢钙 
英文名称:
Phosphoric acid,calcium salt, hydrate (1:1:2)
英文别名:
Phosphoric acid, calcium salt, hydrate (1:1:2);
Phosphoric acid, calcium salt (1:1), dihydrate (8CI,9CI);
Bekapress D 2;
Bonit;
Budit 222;
Calcium hydrogen phosphate (CaHPO4) hydrate (1:2);
Calcium hydrogen phosphate dihydrate;
Calcium monohydrogen orthophosphate dihydrate;
Calcium monohydrogen phosphate dihydrate;
Calcium phosphate (CaHPO4) dihydrate;
Calcium phosphate dihydrate;
Calipharm;
DiTab;
Dibasic calcium phosphate dihydrate;
Dicalcium phosphate dihydrate;
Emcompress;
Emcompress Premium;
Emcompress Special;
Monohydrogen monocalcium phosphate dihydrate;
Parmcompress;
Tri-Compress 
CAS No.:
7789-77-7
分 子 式:
Ca.H3O4P.2H2O
分 子 量:
172.09
精确分子量:
173.96062
PSA:
111.69000
MDL:
MFCD00149621
EINECS:
231-826-1
InChI:
InChI=1/Ca.H3O4P.2H2O/c;1-5(2,3)4;;/h;(H3,1,2,3,4);2*1H2/q+2;;;/p-3
危险品标志:
IrritantXi
风险术语:
R36/37/38;
安全术语:
S26;S36;
分子结构式:
SDS:
查看

磷酸氢钙(二水) 制备方法及用途

制备方法

1.用盐酸或硫酸分解兽骨,再加氢氧化钙,在一定的pH值下沉淀,可得磷酸氢钙,再经过滤、洗涤、干燥可制得成品。 2.以普通过磷酸钙为原料,经多段水萃取、脱氟、石灰乳中和制得。也可由硫酸萃取磷酸经计量后进入脱氟槽,加入脱氟剂脱除氟、砷、铅等过程制得。或者将过磷酸钙粉碎后送入煅烧炉中,在890~1300℃下煅烧,脱氟、脱硫后出料,冷却、粉碎制得。 3.采用磷酸和石灰乳中和法或者磷酸钠盐与氯化钙的复分解反应,反应过程中要注意溶液pH的变化,直至反应终点。生成物溶液经清水洗涤、离心脱水、干燥、粉碎后得成品。 4.将二水合磷酸氢二钠90g(0.5mol)与磷酸二氢钾5g(0.037mol)溶于1L的热水中,将溶液冷却至室温。另外,将六水合氯化钙110g(0.5mol)溶于1L的水中制成溶液。向10g磷酸二氢钾溶于0.5L水所形成的溶液中,将上述两种溶液通过滴液漏斗以同样的速度慢慢滴加,并进行充分搅拌。反应液的pH值最初为4,加入甲基红为指示剂,使其保持pH值为4~5。如果pH值升高,则用磷酸二氢钾溶液调整pH值,以便使其产生沉淀。滴加过程约需2.5至3h。然后,将结晶过滤分离,用330mL磷酸溶液(在1L水中含有45%磷酸0.16mL)洗涤3次,然后用250mL乙醇洗涤,在空气中干燥就可制得二水合物。洗涤操作应快速不间断进行,在20min以内完成。直到洗液的pH值达到5时。

合成制备方法

1.用盐酸或硫酸分解兽骨,再加氢氧化钙,在一定的pH值下沉淀,可得磷酸氢钙,再经过滤、洗涤、干燥可制得成品。

2.以普通过磷酸钙为原料,经多段水萃取、脱氟、石灰乳中和制得。也可由硫酸萃取磷酸经计量后进入脱氟槽,加入脱氟剂脱除氟、砷、铅等过程制得。或者将过磷酸钙粉碎后送入煅烧炉中,在890~1300℃下煅烧,脱氟、脱硫后出料,冷却、粉碎制得。

3.采用磷酸和石灰乳中和法或者磷酸钠盐与氯化钙的复分解反应,反应过程中要注意溶液pH的变化,直至反应终点。生成物溶液经清水洗涤、离心脱水、干燥、粉碎后得成品。

4.将二水合磷酸氢二钠90g(0.5mol)与磷酸二氢钾5g(0.037mol)溶于1L的热水中,将溶液冷却至室温。另外,将六水合氯化钙110g(0.5mol)溶于1L的水中制成溶液。向10g磷酸二氢钾溶于0.5L水所形成的溶液中,将上述两种溶液通过滴液漏斗以同样的速度慢慢滴加,并进行充分搅拌。反应液的pH值最初为4,加入甲基红为指示剂,使其保持pH值为4~5。如果pH值升高,则用磷酸二氢钾溶液调整pH值,以便使其产生沉淀。滴加过程约需2.5至3h。然后,将结晶过滤分离,用330mL磷酸溶液(在1L水中含有45%磷酸0.16mL)洗涤3次,然后用250mL乙醇洗涤,在空气中干燥就可制得二水合物。洗涤操作应快速不间断进行,在20min以内完成。直到洗液的pH值达到5时。

用途简介

缓冲剂;疏松剂;面用改良剂营养增补剂,酵母食料,乳化剂,固化剂,抗氧化增效剂,稳定剂。如作面粉、蛋糕、糕点、焙制品质改良剂。

用途

1.用作饲料添加剂,作为家禽的辅助饲料,以补充畜禽饲料中的磷、钙元素。极易被畜禽消化吸收,使家禽体重增加,以增加产肉量、产乳量、产蛋量,同时还可治疗牲畜的佝偻病、软骨病、贫血症等。作为骨粉的替代升级产品,合理补充畜体磷、钙,全面调节营养平衡,促进畜禽健康生长发育和生产,防治畜禽的软骨病、佝偻病和贫血病等。适用于各种畜禽全价饲料、精饲料、水产饲料、预混料及各种自配料。

2.可用作钙强化剂、乳化稳定剂、面团调理剂、营养增补剂和抗氧化增效剂。

3.补钙剂。能促进骨骼和牙齿的钙化,补充钙质的不足。还可以调节水、电解质及酸碱平衡,维持神经肌肉的正常兴奋性,改善细胞膜的通透性,增加毛细血管壁的致密性。也用于抗过敏、镁中毒、氟中毒的处理。





磷酸氢钙(二水) 物化性质

外观与性状:
白色结晶固体
密度:
2.31
熔点:
109°C -H₂O
沸点:
158ºC at 760 mmHg
折射率:
1.5394
存储条件/存储方法:

1.食品级塑料袋外套编织袋包装。

2.应贮存在通风、干燥、阴凉、清洁的库房内。包装要密封,防潮。不得与有毒物品和其他污染物品共贮混运。运输时要防雨淋和烈日暴晒。装卸时要小心轻放,防止包装破损。失火时,可用水、沙土、各种灭火器进行扑救。

稳定性相关:

有二水磷酸氢钙和无水磷酸氢钙两种。在低于36℃时,二水物是稳定的;高于36℃时,无水物是稳定的。常用的为二水物CaHPO4·2H2O,其相对密度为2.306,微溶于水,不溶于乙醇,易溶于稀盐酸、硝酸、醋酸,在空气中稳定,加热至100℃以上,逐渐失去结晶水,加热至175℃以上转化为CaHPO4,在400~430℃时,失去结晶水而成焦磷酸钙Ca2P2O7。结晶水即使在100℃以下,也会慢慢失去。

其它信息:

1.      性状:白色单斜晶系结晶性粉末。无臭、无味。

2.      密度(g/mL 25ºC):2.306

3.      熔点(ºC):190

4.      溶解性:易缓慢地溶于甘油,微溶于水,不溶于乙醇,易溶于稀盐酸和硝酸。

磷酸氢钙(二水) 安全信息

WGK_Germany:
1
德国有关水污染物质的分类清单
危险类别码:
R36/37/38
安全说明:
S26-S36
安全标志:
S26:万一接触眼睛,立即使用大量清水冲洗并送医诊治。
S36:穿戴合适的防护服装。
危险标志:
Xi:Irritant

磷酸氢钙(二水) 毒理性

毒理学数据:

急性毒性:LD50:4000mg/Kg(大鼠经口);4720mg/Kg(兔经皮)。

                    LC50:9400mg/m3,2小时(小鼠吸入)。

刺激口、鼻、喉和肺,导致味觉、嗅觉衰减,鼻孔出血。

生态数据:

对水是稍微危害的,若无政府许可,勿将材料排入周围环境。

磷酸氢钙(二水) MSDS


Section 1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE
  Product identifiers
    Product name        : Calcium phosphate dibasic dihydrate    
    CAS-No.        : 7789-77-7    
  

Section 2. HAZARDS IDENTIFICATION
  Classification of the substance or mixture
  Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP]
    Skin irritation (Category 2)
    Eye irritation (Category 2)
    Specific target organ toxicity - single exposure (Category 3)
  Classification according to EU Directives 67/548/EEC or 1999/45/EC
    Irritating to eyes, respiratory system and skin.
  Label elements
  Labelling according Regulation (EC) No 1272/2008 [CLP]
    Pictogram
    Signal word        Warning    
    Hazard statement(s)
    Causes skin irritation.
    Causes serious eye irritation.
    May cause respiratory irritation.
    Precautionary statement(s)
    Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
    P305 + P351 + P338        IF IN EYES: Rinse cautiously with water for several minutes. Remove    
    contact lenses, if present and easy to do. Continue rinsing.
    Supplemental Hazard        none    
    Statements
  According to European Directive 67/548/EEC as amended.
    Hazard symbol(s)
    R-phrase(s)
    R36/37/38        Irritating to eyes, respiratory system and skin.    
    S-phrase(s)
    S26        In case of contact with eyes, rinse immediately with plenty of water and    
    seek medical advice.
    S36        Wear suitable protective clothing.    
  Other hazards - none

Section 3. COMPOSITION/INFORMATION ON INGREDIENTS
  Substances
    Formula        : HCaO4P · 2H2O    
    Molecular Weight        : 172,09 g/mol    
    Component        Concentration    
  Calcium hydrogenorthophosphate dihydrate
    CAS-No.        7789-77-7        -    
    EC-No.        231-826-1    

Section 4. FIRST AID MEASURES
  Description of first aid measures
  General advice
    Consult a physician. Show this safety data sheet to the doctor in attendance.
  If inhaled
    If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
  In case of skin contact
    Wash off with soap and plenty of water. Consult a physician.
  In case of eye contact
    Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
  If swallowed
    Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
  Most important symptoms and effects, both acute and delayed
  Indication of any immediate medical attention and special treatment needed
    no data available

Section 5. FIREFIGHTING MEASURES
  Extinguishing media
  Suitable extinguishing media
    Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
  Special hazards arising from the substance or mixture
    Thermal decomposition may produce toxic fumes of phosphorus oxides and/or phosphine
    Oxides of phosphorus, Calcium oxide
  Advice for firefighters
    Wear self contained breathing apparatus for fire fighting if necessary.
  Further information
    no data available

Section 6. ACCIDENTAL RELEASE MEASURES
  Personal precautions, protective equipment and emergency procedures
    Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure
    adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
  Environmental precautions
    Do not let product enter drains.
  Methods and materials for containment and cleaning up
    Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed
    containers for disposal.
  Reference to other sections
    For disposal see section 13.

Section 7. HANDLING AND STORAGE
  Precautions for safe handling
    Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
    Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire
    protection.
  Conditions for safe storage, including any incompatibilities
    Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
  Specific end uses
    no data available

Section 8. EXPOSURE CONTROLS/PERSONAL PROTECTION
  Control parameters
  Components with workplace control parameters
  Exposure controls
  Appropriate engineering controls
    Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and
    at the end of workday.
  Personal protective equipment
  Eye/face protection
    Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested
    and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
  Skin protection
    Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
    (without touching glove's outer surface) to avoid skin contact with this product. Dispose of
    contaminated gloves after use in accordance with applicable laws and good laboratory practices.
    Wash and dry hands.
    The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
    the standard EN 374 derived from it.
  Body Protection
    impervious clothing, The type of protective equipment must be selected according to the
    concentration and amount of the dangerous substance at the specific workplace.
  Respiratory protection
    For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator.For higher
    level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143) respirator cartridges.
    Use respirators and components tested and approved under appropriate government standards
    such as NIOSH (US) or CEN (EU).

Section 9. PHYSICAL AND CHEMICAL PROPERTIES
  Information on basic physical and chemical properties
    a) Appearance        Form: crystalline    
    Colour: white
    b) Odour        no data available    
    c) Odour Threshold        no data available    
    d) pH        no data available    
    e) Melting point/freezing        no data available    
    point
    f) Initial boiling point and no data available
    boiling range
    g) Flash point        no data available    
    h) Evaporation rate        no data available    
    i) Flammability (solid, gas) no data available
    j) Upper/lower        no data available    
    flammability or
    explosive limits
    k) Vapour pressure        no data available    
    l) Vapour density        no data available    
    m) Relative density        2,310 g/cm3    
    n) Water solubility        no data available    
    o) Partition coefficient: n- no data available
    octanol/water
    p) Autoignition        no data available    
    temperature
    q) Decomposition        no data available    
    temperature
    r) Viscosity        no data available    
    s) Explosive properties        no data available    
    t) Oxidizing properties        no data available    
  Other safety information
    no data available

Section 10. STABILITY AND REACTIVITY
  Reactivity
    no data available
  Chemical stability
    no data available
  Possibility of hazardous reactions
    no data available
  Conditions to avoid
    no data available
  Incompatible materials
    Strong oxidizing agents
  Hazardous decomposition products
    Other decomposition products - no data available

Section 11. TOXICOLOGICAL INFORMATION
  Information on toxicological effects
  Acute toxicity
    no data available
  Skin corrosion/irritation
    no data available
  Serious eye damage/eye irritation
    no data available
  Respiratory or skin sensitization
    no data available
  Germ cell mutagenicity
    no data available
  Carcinogenicity
    IARC:        No component of this product present at levels greater than or equal to 0.1% is identified as    
    probable, possible or confirmed human carcinogen by IARC.
  Reproductive toxicity
    no data available
  Specific target organ toxicity - single exposure
    Inhalation - May cause respiratory irritation.
  Specific target organ toxicity - repeated exposure
    no data available
  Aspiration hazard
    no data available
  Potential health effects
  Inhalation        May be harmful if inhaled. Causes respiratory tract irritation.    
  Ingestion        May be harmful if swallowed.    
  Skin        May be harmful if absorbed through skin. Causes skin irritation.    
  Eyes        Causes serious eye irritation.    
  Additional Information
    RTECS: Not available

Section 12. ECOLOGICAL INFORMATION
  Toxicity
    no data available
  Persistence and degradability
    no data available
  Bioaccumulative potential
    no data available
  Mobility in soil
    no data available
  Results of PBT and vPvB assessment
    no data available
  Other adverse effects
    no data available

Section 13. DISPOSAL CONSIDERATIONS
  Waste treatment methods
  Product
    Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed
    professional waste disposal service to dispose of this material. Dissolve or mix the material with a
    combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.
  Contaminated packaging
    Dispose of as unused product.

Section 14. TRANSPORT INFORMATION
  UN number
    ADR/RID: -        IMDG: -        IATA: -    
  UN proper shipping name
    ADR/RID: Not dangerous goods
    IMDG: Not dangerous goods
    IATA:        Not dangerous goods    
  Transport hazard class(es)
    ADR/RID: -        IMDG: -        IATA: -    
  Packaging group
    ADR/RID: -        IMDG: -        IATA: -    
  Environmental hazards
    ADR/RID: no        IMDG Marine pollutant: no        IATA: no    
  Special precautions for user
    no data available

Section 15. REGULATORY INFORMATION
    This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
  Safety, health and environmental regulations/legislation specific for the substance or mixture
    no data available
  Chemical Safety Assessment


SECTION 16 - ADDITIONAL INFORMATION
N/A

磷酸氢钙(二水) 分子结构与计算化学数据

计算化学数据

1.疏水参数计算参考值(XlogP):无

2.氢键供体数量:3

3.氢键受体数量:6

4.可旋转化学键数量:0

5.互变异构体数量:无

6.拓扑分子极性表面积85.4

7.重原子数量:8

8.表面电荷:0

9.复杂度:46.5

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:4

磷酸氢钙(二水) 上游产品

磷酸氢钙(二水) 表征图谱

推荐供应商更多供应商>>

湖北齐飞医药化工有限公司

产品介绍:
产品名称:磷酸氢钙 Cas号:7789-77-7 纯度:99% 包装信息:25kg纸板桶/编织袋/塑料桶 价格:25.0元
联系方式:
联系人:朱梦蝶 电话:027-59322506 手机:18071128683

湖北信康医药化工有限公司

产品介绍:
产品名称:磷酸氢钙二水合物 Cas号:7789-77-7 纯度:99% 包装信息:25kg纸板桶/编织袋/塑料桶 价格:25.0元
联系方式:
联系人:张欢 电话:027-59308705 手机:18827031272

湖北实顺生物科技有限公司

产品介绍:
产品名称:磷酸氢钙 Cas号:7789-77-7 纯度:99% 包装信息:25kg纸板桶/编织袋/塑料桶 价格:25.0元
联系方式:
联系人:张经理 电话:027-59223025 手机:15172526927

湖北永阔科技有限公司

产品介绍:
产品名称:磷酸氢钙 Cas号:7789-77-7 纯度:99% 包装信息:25kg纸板桶/编织袋/塑料桶 价格:25.0元
联系方式:
联系人:徐 电话:027-59223108 手机:15107166787

天门恒昌化工有限公司

产品介绍:
产品名称:磷酸氢钙 Cas号:7789-77-7 纯度:99% 包装信息:25kg纸板桶/编织袋/塑料桶 价格:25.0元
联系方式:
联系人:黄经理 电话:027-59322316 手机:15827039378

湖北常鑫盛化工有限公司

产品介绍:
产品名称:磷酸氢钙 Cas号:7789-77-7 纯度:98% 包装信息:1kg,25kg,桶装 价格:0.0元 - 100.0元
联系方式:
联系人:黄 电话:18971203904 手机:18971203904

湖北云镁科技有限公司

产品介绍:
产品名称:磷酸氢钙 二水合物 Cas号:7789-77-7 纯度:99% 包装信息:25kg纸板桶/编织袋/塑料桶,10kg铝听/纸箱,1kg铝箔袋/氟化瓶 价格:1.0元 - 25.0元
联系方式:
联系人:方经理 电话:027-59206672 手机:18327059871

武汉卡诺斯科技有限公司

产品介绍:
产品名称:二水磷酸氢钙 Cas号:7789-77-7 纯度:99% 包装信息:1千克,15千克,20千克,30千克 价格:10.0元 - 30.0元
联系方式:
联系人:尚文 电话:153-37111468 手机:15337111468

湖北万得化工有限公司

产品介绍:
产品名称:磷酸氢钙 Cas号:7789-77-7 纯度:99% 包装信息:1t吨袋,200kg镀锌铁桶/塑料桶,25kg纸板桶/编织袋/塑料桶,10kg铝听/纸箱,1kg铝箔袋/氟化瓶 价格:1.0元 - 1,000.0元
联系方式:
联系人:王念 电话:027-59210159 手机:15172311821

湖北鑫红利化工有限公司

产品介绍:
产品名称:二水磷酸氢钙 Cas号:7789-77-7 纯度:99% 包装信息:1t吨袋,200kg镀锌铁桶/塑料桶,25kg纸板桶/编织袋/塑料桶,10kg铝听/纸箱,1kg铝箔袋/氟化瓶 价格:1.0元 - 1,000.0元
联系方式:
联系人:周女士 电话:027-59503710 手机:18871490254