1,2-二甲基-5-苯基-4-(喹唑啉-4-基氨基)吡唑-3-酮

  • 基本信息
  • 物化性质
  • 毒理性

1,2-二甲基-5-苯基-4-(喹唑啉-4-基氨基)吡唑-3-酮 基本信息

中文名称:
1,2-二甲基-5-苯基-4-(喹唑啉-4-基氨基)吡唑-3-酮 
中文别名:
2,5-dimethyl-1-phenyl-4-(quinazolin-4-ylamino)pyrazol-3-one 
英文名称:
3H-Pyrazol-3-one,1,2-dihydro-1,5-dimethyl-2-phenyl-4-(4-quinazolinylamino)-
英文别名:
2,5-dimethyl-1-phenyl-4-(quinazolin-4-ylamino)pyrazol-3-one;
3H-Pyrazol-3-one,1,2-dihydro-1,5-dimethyl-2-phenyl-4-(4-quinazolinylamino)- 
CAS No.:
100330-91-4
分 子 式:
C19H17N5O
分 子 量:
0
精确分子量:
331.14300
PSA:
64.74000
分子结构式:
SDS:
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1,2-二甲基-5-苯基-4-(喹唑啉-4-基氨基)吡唑-3-酮 物化性质

密度:
1.345g/cm3
沸点:
514ºC at 760mmHg
闪点:
264.7ºC
折射率:
1.725
蒸汽压:
1.12E-10mmHg at 25°C

1,2-二甲基-5-苯基-4-(喹唑啉-4-基氨基)吡唑-3-酮 毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UR0450000
CHEMICAL NAME :
3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-2-phenyl-4-(4-quinazolinylam ino)-
CAS REGISTRY NUMBER :
100330-91-4
LAST UPDATED :
199103
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C19-H17-N5-O
MOLECULAR WEIGHT :
331.41

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
369 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 51,100,1988
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
336 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 51,100,1988
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
390 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 51,100,1988
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
292 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 51,100,1988
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
78 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 53,94,1990

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