盐酸氨吖啶; 9-氨基吖啶盐酸盐

  • 基本信息
  • 物化性质
  • 安全信息
  • 毒理性
  • MSDS
  • 海关数据
  • 结构与计算化学
  • 表征图谱

盐酸氨吖啶; 9-氨基吖啶盐酸盐 基本信息

中文名称:
盐酸氨吖啶; 9-氨基吖啶盐酸盐 
中文别名:
盐酸氨吖啶;
9-氨基吖啶盐酸盐 
英文名称:
9-Acridinamine,hydrochloride (1:1)
英文别名:
9-Acridinamine, hydrochloride (1:1);
9-Acridinamine, monohydrochloride (9CI);
Acridine, 9-amino-, monohydrochloride (8CI);
9-Aminoacridine hydrochloride;
9-Aminoacridine monohydrochloride;
Acramine yellow;
Aminacrine hydrochloride;
Monacrin hydrochloride 
CAS No.:
134-50-9
分 子 式:
C13H10N2.ClH
分 子 量:
230.69
精确分子量:
230.06108
PSA:
38.91000
EINECS:
205-145-5
InChI:
InChI=1/C13H10N2.ClH.H2O/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13;;/h1-8H,(H2,14,15);1H;1H2
分子结构式:
SDS:
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盐酸氨吖啶; 9-氨基吖啶盐酸盐 物化性质

外观与性状:
淡黄色晶体,有香味的物质
密度:
1.268g/cm3
沸点:
413.5ºC at 760mmHg
闪点:
233.2ºC
蒸汽压:
4.76E-07mmHg at 25°C
存储条件/存储方法:
库房通风低温干燥

盐酸氨吖啶; 9-氨基吖啶盐酸盐 安全信息

海关代码:
2933990090

盐酸氨吖啶; 9-氨基吖啶盐酸盐 毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AR7350000
CHEMICAL NAME :
Acridine, 9-amino-, hydrochloride
CAS REGISTRY NUMBER :
134-50-9
LAST UPDATED :
199701
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C13-H10-N2.Cl-H
MOLECULAR WEIGHT :
230.71
WISWESSER LINE NOTATION :
T C666 BNJ IZ &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
78 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
DNA adduct
TEST SYSTEM :
Mammal - species unspecified Lymphocyte
DOSE/DURATION :
10 pph
REFERENCE :
BIPMAA Biopolymers. (John Wiley & Sons, Inc., 605 Third Ave., New York, NY 10158) V.1- 1963- Volume(issue)/page/year: 11,2537,1972 *** REVIEWS *** TOXICOLOGY REVIEW FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 13,747,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 04770 No. of Facilities: 68 (estimated) No. of Industries: 1 No. of Occupations: 6 No. of Employees: 2770 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 04770 No. of Facilities: 9 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 166 (estimated) No. of Female Employees: 105 (estimated)

盐酸氨吖啶; 9-氨基吖啶盐酸盐 MSDS

Name: 9-Aminoacridine hydrochloride monohydrate 98% Material Safety Data Sheet
Synonym: Aminacrine hydrochloride
CAS: 134-50-9
Section 1 - Chemical Product   MSDS Name:9-Aminoacridine hydrochloride monohydrate 98% Material Safety Data Sheet
Synonym:Aminacrine hydrochloride

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
134-50-9 9-Aminoacridine hydrochloride monohydr >99 unlisted
Hazard Symbols: T
Risk Phrases: 25 40

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
Toxic if swallowed. Limited evidence of a carcinogenic effect.The toxicological properties of this material have not been fully investigated.Possible risks of irreversible effects.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
May cause skin irritation.
Ingestion:
Harmful if swallowed. May cause irritation of the digestive tract.
The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
Possible risk of irreversible effects.

Section 4 - FIRST AID MEASURES
  Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Section 7 - HANDLING and STORAGE
  Handling:
Wash thoroughly after handling. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 134-50-9: CAS# 52417-22-8: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Powder
Color: yellow
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 300 deg C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: 0.33g/100 ml water
Specific Gravity/Density: >1.0
Molecular Formula: C13H10N2.HCl.H2O
Molecular Weight: 248.71

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Dust generation, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong bases, acid anhydrides.
Hazardous Decomposition Products:
Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 134-50-9: AR7350000 CAS# 52417-22-8: AR6850000 LD50/LC50:
CAS# 134-50-9: Oral, mouse: LD50 = 78 mg/kg.
CAS# 52417-22-8.
Carcinogenicity:
9-Aminoacridine hydrochloride - Not listed by ACGIH, IARC, or NTP.
9-Aminoacridine hydrochloride monohydrate - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
 

Section 13 - DISPOSAL CONSIDERATIONS
  Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
 
IATA
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.*
Hazard Class: 6.1
UN Number: 2811
Packing Group: III
IMO
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2811
Packing Group: III
RID/ADR
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2811
Packing group: III

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T
Risk Phrases:
R 25 Toxic if swallowed.
R 40 Limited evidence of a carcinogenic effect.
Safety Phrases:
S 22 Do not breathe dust.
S 24/25 Avoid contact with skin and eyes.
S 28A After contact with skin, wash immediately with
plenty of water.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 134-50-9: No information available.
CAS# 52417-22-8: No information available.
Canada
CAS# 134-50-9 is listed on Canada's NDSL List.
CAS# 134-50-9 is not listed on Canada's Ingredient Disclosure List.
CAS# 52417-22-8 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 134-50-9 is listed on the TSCA inventory.
CAS# 52417-22-8 is not on the TSCA Inventory because it is a hydrate.
It is considered to be listed if the CAS number for the anhydrous form
is on the inventory (40CFR720.3(u)(2)).


SECTION 16 - ADDITIONAL INFORMATION
N/A

盐酸氨吖啶; 9-氨基吖啶盐酸盐 海关数据

中国海关编码:2933990090

概述:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素:
品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
摘要/Summary:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

盐酸氨吖啶; 9-氨基吖啶盐酸盐 分子结构与计算化学数据

分子结构数据

1、  摩尔折射率:64.26

2、  摩尔体积(cm3/mol):153.1

3、  等张比容(90.2K):434.9

4、  表面张力(dyne/cm):65.0

5、  极化率(10-24cm3):25.47

计算化学数据

1.疏水参数计算参考值(XlogP):无

2.氢键供体数量:2

3.氢键受体数量:2

4.可旋转化学键数量:0

5.互变异构体数量:2

6.拓扑分子极性表面积38.9

7.重原子数量:16

8.表面电荷:0

9.复杂度:207

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:2

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