美替沙腙

  • 基本信息
  • 物化性质
  • 安全信息
  • 毒理性
  • MSDS
  • 海关数据
  • 结构与计算化学
  • 上游产品

美替沙腙 基本信息

中文名称:
美替沙腙 
中文别名:
美替沙腙;
肼硫代羰酰胺,2-(1,2-二氢-1-甲基-2-氧代-3H-吲哚-3-亚基) 
英文名称:
Methisazone
英文别名:
Metisazone;
Metisazon;
Viruzona;
Metisazonum;
N-methylisatin-3-thiosemicarbazone;
methisazone;
[(1-methyl-2-oxoindol-3-ylidene)amino]thiourea;
[(Z)-(1-methyl-2-oxoindol-3-ylidene)amino]thiourea;
Marboran;
N-Methylisatin thiosemicarbazone;
Kemoviran 
CAS No.:
1910-68-5
分 子 式:

C10H10N4OS

分 子 量:
234.28
精确分子量:
234.05800
PSA:
102.81000
EINECS:
217-616-2
危险品标志:

 

风险术语:

 

安全术语:

 

分子结构式:
SDS:
查看

美替沙腙 物化性质

密度:
1.47 g/cm3
沸点:
410.3ºC at 760 mmHg
闪点:
202ºC
折射率:
1.732
蒸汽压:
6.07E-07mmHg at 25°C

美替沙腙 安全信息

海关代码:
2933790090

美替沙腙 毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NL7960000
CHEMICAL NAME :
Indole-2,3-dione, 1-methyl-, 3-(thiosemicarbazone)
CAS REGISTRY NUMBER :
1910-68-5
LAST UPDATED :
199106
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C10-H10-N4-O-S
MOLECULAR WEIGHT :
234.30
WISWESSER LINE NOTATION :
T56 BNVYJ B1 DUNMYZUS

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>50 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
56 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
DNA damage
TEST SYSTEM :
Human HeLa cell
DOSE/DURATION :
30 umol/L
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 25,821,1976

美替沙腙 MSDS

Name: n-Methylisatin 3-(thiosemicarbazone) 96% Material Safety Data Sheet
Synonym: Methisazon
CAS: 1910-68-5
Section 1 - Chemical Product   MSDS Name:n-Methylisatin 3-(thiosemicarbazone) 96% Material Safety Data Sheet
Synonym:Methisazon

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
1910-68-5 N-Methylisatin 3-(thiosemicarbazone), 217-616-2
Hazard Symbols: Not available.
Risk Phrases:

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
Appearance: Target Organs: None.
Potential Health Effects
The toxicological properties of this material have not been investigated. Use appropriate procedures to prevent opportunities for direct contact with the skin or eyes and to prevent inhalation.

Section 4 - FIRST AID MEASURES
  Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Remove contaminated clothing and shoes.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up, then place into a suitable container for disposal.

Section 7 - HANDLING and STORAGE
  Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Storage:
Store in a cool, dry place. Keep container closed when not in use.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits. Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels.
Exposure Limits +--------------------+-------------------+-------------------+-----------------+ | Chemical Name | ACGIH | NIOSH |OSHA - Final PELs| |--------------------|-------------------|-------------------|-----------------| | N-Methylisatin 3-(t|none listed |none listed |none listed | | hiosemicarbazone), | | | | | 96% | | | | +--------------------+-------------------+-------------------+-----------------+ OSHA Vacated PELs: N-Methylisatin 3-(thiosemicarbazone), 96%: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment Eyes: Wear safety glasses and chemical goggles if splashing is possible.
Skin:
Wear appropriate protective gloves and clothing to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Not available.
Appearance: not available
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: @ 760.00mm Hg
Freezing/Melting Point: 235 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
NFPA Rating: Not published.
Explosion Limits, Lower: Not available.
Upper: Not available.
Decomposition Temperature:
Solubility:
Specific Gravity/Density:
Molecular Formula: C10H10N4OS
Molecular Weight: 234.28

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, strong oxidants.
Incompatibilities with Other Materials:
Not available.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide, nitrogen.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 1910-68-5: NL7960000 LD50/LC50:
CAS# 1910-68-5: Oral, mouse: LD50 = 4 gm/kg.
Carcinogenicity:
N-Methylisatin 3-(thiosemicarbazone), 96% - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
 

Section 13 - DISPOSAL CONSIDERATIONS
  Chemical waste generators must determine whether a discarded chemical is classif as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Part Additionally, waste generators must consult state and local hazardous waste regu ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - TRANSPORT INFORMATION
 
CDG/CPL
Not classified as hazardous for supply.
Canadian TDG
No information available.

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 1910-68-5: No information available.
United Kingdom Occupational Exposure Limits
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
WHMIS: Not available.
CAS# 1910-68-5 is not listed on Canada's Ingredient Disclosure List.
Exposure Limits
US FEDERAL
TSCA
CAS# 1910-68-5 is not listed on the TSCA inventory.
It is for research and development use only.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
Section 302 (RQ)
None of the chemicals in this material have an RQ.
Section 302 (TPQ)
None of the chemicals in this product have a TPQ.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.


SECTION 16 - ADDITIONAL INFORMATION
N/A

美替沙腙 海关数据

中国海关编码:2933790090

概述:
2933790090 其他内酰胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:9.0% 普通关税:20.0%
申报要素:
品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
摘要/Summary:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

美替沙腙 分子结构与计算化学数据

计算化学数据

1.疏水参数计算参考值(XlogP):无

2.氢键供体数量:2

3.氢键受体数量:3

4.可旋转化学键数量:1

5.互变异构体数量:7

6.拓扑分子极性表面积:103

7.重原子数量:16

8.表面电荷:0

9.复杂度:355

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:1

14.不确定化学键立构中心数量:0

15.共价键单元数量:1

美替沙腙 上游产品

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湖北恩星生物科技有限公司

产品介绍:
产品名称:美替沙腙 Cas号:1910-68-5 纯度: 包装信息:100kg,200kg,300kg,400kg,500kg 价格:64.0元 - 100.0元
联系方式:
联系人:邵经理 电话:16621771607 手机:16621771607