茶多酚

  • 基本信息
  • 制备方法及用途
  • 物化性质
  • 安全信息
  • 毒理性
  • MSDS

茶多酚 基本信息

中文名称:
茶多酚 
中文别名:
茶多酚;
绿茶提取物;
茶(CAMELLIA SINENSIS)叶提取物;
茶叶萃取物;
(一)-EPIGALLOCATECHING GALLATE;
(一)-表儿茶素没食子酸酯;
维多酚;
绿茶植物提取物 
英文名称:
Tea polyphenol
英文别名:
TEA POLYPHENOL;
Camellia sinensis;
Tea polyphenols 
CAS No.:
84650-60-2
分 子 式:

C17H19N3O

分 子 量:
281.36
精确分子量:
458.08500
PSA:
197.37000
EINECS:
200-053-1
危险品标志:

 

风险术语:

 

安全术语:

 

分子结构式:
SDS:
查看

茶多酚 制备方法及用途

合成制备方法

溶剂萃取法
取当年的茶叶末或老茶叶粉碎过0.75mm筛,加入10倍量的清水,在90℃下搅拌浸提l0min。趁热过滤后,滤渣再浸提2次;合并3次滤液,加人等体积的氯仿搅拌萃取30min,静置分层后,取水相,加入3倍量的乙酸乙酯,先后抽提3次,每次20min。静置分层,收集有机相,减压蒸馏回收乙酸乙酯;残液浓缩至干,冷却后冷冻干燥得白色粉状品,收率29%。

由茶叶以1:15加入pH值4~5的酸性水中,在120℃下煮30min,过滤,合并两次滤液,浓缩、活性炭脱色、离心分离、真空干燥而得。得率可达28.9%(纯度72%)。或由绿茶用温水提取后用二氯甲烷提掉咖啡因,再用乙酸乙酯水溶液(2:1)提取,离子交换树脂吸附、丙酮水溶液解吸等精制而成。得率约8%~9%。

用途

茶多酚具有抗氧化作用和抗衰老、降血脂等一系列很好的药理功能。我国规定可用于糕点馅、油脂和火腿,最大使用量为0.4g/kg;用于肉制品和鱼制品,最大使用量为0.3g/kg;用于油炸食品和方便面,最大使用量为0.2g/kg(以油脂中的儿茶素计);用于含油脂酱料,最大使用量为0.lg.kg。食品工业用于抗氧化、保鲜、祛臭,医药工业上用于抗菌、抗癌、抗衰老,日化产品上作特殊功能添加剂。

茶多酚 物化性质

外观与性状:
黄绿色自由流动粉末
稳定性相关:

淡黄至茶褐色略带茶香的水溶液、灰白色粉状固体或结晶,具涩味。易溶于水、乙醇、乙酸乙酯,微溶于油脂。对热、酸较稳定,2%溶液加热至120℃并保持30min,无明显改变,在160℃:油脂中30rain降解20%,2%溶液在37℃下保持3天后,在pH值2~7范围内稳定,pH>7和光照下易氧化聚合。2%茶多酚在2%、5%和10%食盐溶液中于pH=6.5、室温下保存3天,其含量无变化。遇铁变绿黑色络合物。略有吸潮性,水溶液pH值为3~4,在碱性条件下易氧化褐变。

茶多酚 安全信息

海关代码:
3824909990

茶多酚 毒理性

毒理学数据:

LD50(2496±32)mg/kg(大鼠,经口)。95%以上的精品为3.94g/kg(大鼠,经口)。
致突变试验Ames试验、骨髓微核实验和骨髓细胞染色体畸变试验表明,在1/20 LD50浓度内均无不良影响,无任何副作用。
按成人剂量20~40倍喂狗3个月,各项血液指标及尿检均无异常。
果蝇终生饲养和小白鼠喂养试验表明,对果蝇的生长、发育和寿命与对小白鼠的血红蛋白、红细胞数、白细胞数、胸腺、脾脏细胞数、肝脏量及体重均无不良影响。

茶多酚 MSDS


Section 1. Chemical Product and Company Identification
    Green Tea Extract
    Common Name/
    Trade Name
    Manufacturer
    Commercial Name(s)
    Synonym
    Chemical Name
    Chemical Family
    Green Tea Extract

Section 4. First Aid Measures
    Eye Contact        Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at    
    least 15 minutes. Cold water may be used. Get medical attention if irritation occurs.
    Skin Contact        Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.    
    Cold water may be used.
    Serious Skin Contact        Not available.    
    Inhalation        If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get    
    medical attention.
    Serious Inhalation        Not available.    
    Ingestion        Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an    
    unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight
    clothing such as a collar, tie, belt or waistband.
    Serious Ingestion        Not available.    

Section 5. Fire and Explosion Data
    Flammability of the Product May be combustible at high temperature.
    Auto-Ignition Temperature Not available.
    Flash Points        Not available.    
    Flammable Limits        Not available.    
    Not available.
    Products of Combustion
    Fire Hazards in Presence of Slightly flammable to flammable in presence of open flames and sparks, of heat.
    Various Substances        Non-flammable in presence of shocks.    
    Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
    of Various Substances        Risks of explosion of the product in presence of static discharge: Not available.    
    Fire Fighting Media        SMALL FIRE: Use DRY chemical powder.    
    and Instructions        LARGE FIRE: Use water spray, fog or foam. Do not use water jet.    
    Special Remarks on        Not available.    
    Fire Hazards
    Special Remarks on Explosion Not available.
    Hazards

Section 6. Accidental Release Measures
    Small Spill        Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by    
    spreading water on the contaminated surface and dispose of according to local and regional authority
    requirements.
    Large Spill
    Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water
    on the contaminated surface and allow to evacuate through the sanitary system.
    Green Tea Extract

Section 7. Handling and Storage
    Precautions        Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the    
    residue under a fume hood. Ground all equipment containing material. Do not breathe dust. Keep away from
    incompatibles such as oxidizing agents.
    Storage        Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 24°C (75.2°F).    

Section 8. Exposure Controls/Personal Protection
    Engineering Controls        Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below    
    recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
    airborne contaminants below the exposure limit.
    Personal Protection        Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.    
    Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used
    a Large Spill        to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist    
    BEFORE handling this product.
    Exposure Limits        Not available.    

Section 9. Physical and Chemical Properties
    Physical state and appearance Solid.        Odor        Characteristic. Tea-like    
    Taste        Not available.    
    Molecular Weight        Not available.    
    Color        Brown. (Light.)    
    pH (1% soln/water)        Not available.    
    >176.67°C (350°F)
    Boiling Point
    Melting Point        Not available.    
    Not available.
    Critical Temperature
    Specific Gravity        Not available.    
    Vapor Pressure        Not applicable.    
    Vapor Density        Not available.    
    Volatility        Not available.    
    Odor Threshold        Not available.    
    Water/Oil Dist. Coeff.        Not available.    
    Ionicity (in Water)        Not available.    
    Dispersion Properties        See solubility in water.    
    Solubility        Soluble in cold water, hot water.    

Section 10. Stability and Reactivity Data
    The product is stable.
    Stability
    Instability Temperature        Not available.    
    Conditions of Instability        Excess heat, incompatible materials    
    Reactive with oxidizing agents.
    Incompatibility with various
    substances
    Not available.
    Corrosivity
    Green Tea Extract
    Incompatible with strong oxidizing agents.
    Special Remarks on
    Reactivity
    Not available.
    Special Remarks on
    Corrosivity
    Polymerization        Will not occur.    

Section 11. Toxicological Information
    Routes of Entry        Inhalation. Ingestion.    
    Toxicity to Animals        LD50: Not available.    
    LC50: Not available.
    Chronic Effects on Humans Not available.
    Other Toxic Effects on
    Slightly hazardous in case of skin contact (irritant), of inhalation.
    Humans
    Special Remarks on        Not available.    
    Toxicity to Animals
    Special Remarks on        Not available.    
    Chronic Effects on Humans
    Special Remarks on other        Acute Potential Heath Effects:    
    Toxic Effects on Humans        Skin: May cause skin irritation.    
    Eyes: Dust may cause mechanical irritation to the eyes.
    Inhalation: Dust may cause respiratory tract irritation.
    Ingestion: Ingestion of large amounts may cause gastrointestinal tract irritation.
    Chronic Potential Health Effects: no information found at this time.
    The toxicological properties of this substance have not been fully investigated.

Section 12. Ecological Information
    Ecotoxicity        Not available.    
    BOD5 and COD        Not available.    
    Possibly hazardous short term degradation products are not likely. However, long term degradation products may
    Products of Biodegradation
    arise.
    Toxicity of the Products        Not available.    
    of Biodegradation
    Special Remarks on the        Not available.    
    Products of Biodegradation

Section 13. Disposal Considerations
    Waste Disposal        Waste must be disposed of in accordance with federal, state and local environmental    
    control regulations.

Section 14. Transport Information
    DOT Classification        Not a DOT controlled material (United States).    
    Identification        Not applicable.    
    Special Provisions for        Not applicable.    
    Transport
    Green Tea Extract
    DOT (Pictograms)

Section 15. Other Regulatory Information and Pictograms
    No products were found.
    Federal and State
    Regulations
    California
    Proposition 65
    Warnings
    Other Regulations        Not available.    
    WHMIS (Canada) Not controlled under WHMIS (Canada).
    Other Classifications
    DSCL (EEC)        This product is not classified according Not applicable.    
    to the EU regulations.
    Health Hazard
    HMIS (U.S.A.)        1 National Fire Protection    
    1 Flammability
    1 Association (U.S.A.)
    Fire Hazard
    1 0 Reactivity
    Health
    Reactivity
    0
    Specific hazard
    Personal Protection
    E
    WHMIS (Canada)
    (Pictograms)
    DSCL (Europe)
    (Pictograms)
    TDG (Canada)
    (Pictograms)
    ADR (Europe)
    (Pictograms)
    Protective Equipment
    Gloves.
    Lab coat.
    Dust respirator. Be sure to use an
    approved/certified respirator or
    equivalent.
    Green Tea Extract


SECTION 16 - ADDITIONAL INFORMATION
N/A

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