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丙萘洛尔 基本信息
- 中文名称:
- 丙萘洛尔
- 中文别名:
- 丙萘洛尔
- 英文名称:
- 2-Naphthalenemethanol, a-[[(1-methylethyl)amino]methyl]-
- 英文别名:
- (+/-)-Pronethalol;
1-naphthalen-2-yl-2-(propan-2-ylamino)ethanol
- CAS No.:
- 54-80-8
- 分 子 式:
- C15H19NO
- 分 子 量:
- 229.35
- 精确分子量:
- 229.14700
- PSA:
- 32.26000
- InChI:
- The Key: HRSANNODOVBCST-UHFFFAOYSA-N
- 安全术语:
- Poison by ingestion, intravenous, and intraperitoneal routes. Questionable carcinogen with experimental carcinogenic and tumorigenic data. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
- 分子结构式:
-
- SDS:
- 查看
丙萘洛尔 物化性质
- 密度:
- 1.074g/cm3
- 沸点:
- 322.4ºC at 760mmHg
- 闪点:
- 84.3ºC
丙萘洛尔 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QJ9100000
- CHEMICAL NAME :
- 2-Naphthalenemethanol,
alpha-((isopropylamino)methyl)-
- CAS REGISTRY NUMBER :
- 54-80-8
- LAST UPDATED :
- 199512
- DATA ITEMS CITED :
- 13
- MOLECULAR FORMULA :
- C15-H19-N-O
- MOLECULAR WEIGHT :
- 229.35
- WISWESSER LINE NOTATION :
- L66J CYQ1MY1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 900 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - acute pulmonary edema
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 45 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - acute pulmonary edema
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 337 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay)
Behavioral - ataxia
Lungs, Thorax, or Respiration - respiratory stimulation
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 124 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay)
Behavioral - ataxia
Lungs, Thorax, or Respiration - respiratory stimulation
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 28800 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 15 gm/kg/30W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria
Blood - leukemia
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 28080 mg/kg/33W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Blood - lymphoma, including Hodgkin's disease
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Endocrine - tumors
Blood - lymphoma, including Hodgkin's disease
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 72 gm/kg/43W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Blood - tumors
Reproductive - Tumorigenic effects - uterine tumors
MUTATION DATA
- TYPE OF TEST :
- Unscheduled DNA synthesis
- TEST SYSTEM :
- Human HeLa cell
- DOSE/DURATION :
- 100 umol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
38,2621,1978
*** REVIEWS ***
TOXICOLOGY REVIEW
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year:
6,395,1986
丙萘洛尔 海关数据
中国海关编码:2922199090
- 概述:
- 2922199090. 其他氨基醇及其醚,酯和它们的盐(但含一种以上含氧基的除外). 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
- 申报要素:
- 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
- 摘要/Summary:
- 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
上海吉至生化科技有限公司
- 产品介绍:
-
产品名称:普罗纳赛洛
Cas号:54-80-8
纯度:99%
包装信息:5mgea,10mgea
价格:498.0元 - 848.0元
- 联系方式:
-
联系人:江珊
电话:021-57520831
手机:15316869680
范德(北京)生物科技有限责任公司
- 产品介绍:
-
产品名称:54-80-8
Cas号:54-80-8
纯度:
包装信息:10mg
价格:2,322.0元
- 联系方式:
-
联系人:王
电话:15911056312
手机:15911056312