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羟哌氯丙嗪亚砜氯吩嗪亚砜 基本信息
- 中文名称：
- 羟哌氯丙嗪亚砜氯吩嗪亚砜
- 中文别名：
- 羟哌氯丙嗪亚砜氯吩嗪亚砜
- 英文名称：
- 1-Piperazineethanol,4-[3-(2-chloro-5-oxido-10H-phenothiazin-10-yl)propyl]-
- 英文别名：
- PERPHENAZINE SULFOXIDE (100 MG);
4-(3-(2-chlorophenothiazin-10-yl)propyl)-1-piperazineethanosulfoxide;
2-chloro-10-(3-(4-(2-hydroxyethyl)-7-piperazinyl)propyl)phenothiazine;
10-[3-[4-(2-Hydroxyethyl)-1-piperazinyl]propyl]-2-chloro-10H-phenothiazine 5-oxide;
etaperazine S-oxide;
1-Piperazineethanol,4-(3-(2-chlorophenothiazin-10-yl)propyl)-,sulfoxide;
Perphenazine Sulfate;
perphenazine sulfoxide;
Perphenazinsulfoxid;
perpherazine sulfoxide
- CAS No.：
- 10078-25-8
- 分 子 式：
- C21H26ClN3O2S
- 分 子 量：
- 0
- 精确分子量：
- 419.14300
- PSA：
- 66.23000
- InChI：
- The Key: WXJXTMQMAOYROI-UHFFFAOYSA-N
- 分子结构式：
-
- SDS：
- 查看
羟哌氯丙嗪亚砜氯吩嗪亚砜 物化性质
- 密度：
- 1.41g/cm3
- 沸点：
- 624.8ºC at 760mmHg
- 闪点：
- 331.7ºC
- 折射率：
- 1.71
- 蒸汽压：
- 1.78E-16mmHg at 25°C
羟哌氯丙嗪亚砜氯吩嗪亚砜 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TL7700000
- CHEMICAL NAME :
- 1-Piperazineethanol,
4-(3-(2-chlorophenothiazin-10-yl)propyl)-, sulfoxide
- CAS REGISTRY NUMBER :
- 10078-25-8
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C21-H26-Cl-N3-O2-S
- MOLECULAR WEIGHT :
- 420.01
- WISWESSER LINE NOTATION :
- T C666 BN ISJ EG IO B3- AT6N DNTJ D2Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,37,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 80 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,37,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1320 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,37,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 127 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,37,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 69 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,37,1972
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Gastrointestinal - hypermotility, diarrhea
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 10,638,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 68 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,37,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Bird - pigeon
- DOSE/DURATION :
- 52500 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,37,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Bird - pigeon
- DOSE/DURATION :
- 450 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,37,1972
