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异三尖杉酯碱 基本信息
- 中文名称：
- 异三尖杉酯碱
- 中文别名：
- 异三尖杉酯碱
- 英文名称：
- Cephalotaxine,3-[4-methyl (2R,3S)-2,3-dihydroxy-2-(3-methylbutyl)butanedioate]
- 英文别名：
- Isoharringtonine;
iso-harringtonine
- CAS No.：
- 26833-86-3
- 分 子 式：
- C28H37NO9
- 分 子 量：
- 531.66
- 精确分子量：
- 531.24700
- PSA：
- 123.99000
- InChI：
- The Key: CAOHZEUEVKYHPF-UHFFFAOYSA-N
- 安全术语：
- Poison by ingestion, subcutaneous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx.
- 分子结构式：
-
- SDS：
- 查看
异三尖杉酯碱 物化性质
- 密度：
- 1.35g/cm3
- 沸点：
- 632.5ºC at 760mmHg
- 折射率：
- 1.607
- 蒸汽压：
- 7.21E-17mmHg at 25°C
异三尖杉酯碱 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NR2935500
- CHEMICAL NAME :
- Isoharringtonine
- CAS REGISTRY NUMBER :
- 26833-86-3
- LAST UPDATED :
- 198909
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C28-H37-N-O9
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 27950 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NCISP* National Cancer Institute Screening Program Data Summary,
Developmental Therapeutics Program. (Bethesda, MD 20205)
Volume(issue)/page/year: JAN1986
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 14600 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. Ireland
Ltd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year:
24,1,1988
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 26110 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NCISP* National Cancer Institute Screening Program Data Summary,
Developmental Therapeutics Program. (Bethesda, MD 20205)
Volume(issue)/page/year: JAN1986
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 13200 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. Ireland
Ltd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year:
24,1,1988
