醋酸铬

  • 基本信息
  • 制备方法及用途
  • 物化性质
  • 安全信息
  • 毒理性
  • MSDS
  • 结构与计算化学
  • 上游产品
  • 下游产品

醋酸铬 基本信息

中文名称:
醋酸铬 
中文别名:
乙酸铬;
醋酸铬 
英文名称:
Acetic acid,chromium(3+) salt (3:1)
英文别名:
Chromic acetate;
NA-9101;
chromicacetate(iii);
acetic acid,chromium (III)-acetate;
Chromium triacetate;
chromium(lll) acetate;
chromium acetate;
cromium acetate;
Chromic Acetate;
chromium(III) acetate;
chromium(III) ethanoate;
CHROME ACETATE;
ChromicAcetatePure;
chromic triacetate 
CAS No.:
1066-30-4
分 子 式:
C2H4O2.1/3Cr
分 子 量:
229.13
精确分子量:
228.98000
PSA:
78.90000
EINECS:
213-909-4
InChI:
The Key: OODUAYRDJZLICL-UHFFFAOYSA-M
风险术语:
36/37/38
分子结构式:
SDS:
查看

醋酸铬 制备方法及用途

制备方法

1.往六水合三氯化铬[Cr(H2O)6Cl3]的稀水溶液中加入稀氨水,煮沸而生成氢氧化铬(需要新鲜制备、并经充分水洗而不含氯离子的)。往其中加入过量的乙酸。反应进行时放出大量的热。数小时后析出结晶,可从母液中分离出结晶,并用丙酮和乙醚充分洗涤,置于硫酸干燥器中干燥。 2. 将氢氧化铬溶于乙酸中反应而得:

合成制备方法

1.往六水合三氯化铬[Cr(H2O)6Cl3]的稀水溶液中加入稀氨水,煮沸而生成氢氧化铬(需要新鲜制备、并经充分水洗而不含氯离子的)。往其中加入过量的乙酸。反应进行时放出大量的热。数小时后析出结晶,可从母液中分离出结晶,并用丙酮和乙醚充分洗涤,置于硫酸干燥器中干燥。

2. 将氢氧化铬溶于乙酸中反应而得:

用途简介

1.有机合成做催化剂及制造铬催化剂;印染工业用于印染羊毛,棉花,丝绸,人造纤维的媒染剂;用于电影,照相,底片冲击,放映及做鞣革剂;三价铬电镀用铬试剂。 2.用作分析试剂,媒染剂,催化剂。

用途

1.有机合成做催化剂及制造铬催化剂;印染工业用于印染羊毛,棉花,丝绸,人造纤维的媒染剂;用于电影,照相,底片冲击,放映及做鞣革剂;三价铬电镀用铬试剂。

2.用作分析试剂,媒染剂,催化剂。

醋酸铬 物化性质

外观与性状:
淡灰色绿色至带蓝色的绿色粉末
密度:
1,28 g/cm3
沸点:
117.1ºC at 760 mmHg
闪点:
40ºC
水溶解性:
slightly soluble
存储条件/存储方法:
库房低温,通风,干燥
稳定性相关:

易溶于水。本品实际是水合醋酸盐[Cr(H2O)6](CH3COO)3。

其它信息:

1.      性状:为蓝紫色的针状结晶。

2.      密度(g/cm3 ):1.28

3.      相对蒸汽密度(g/mL,空气=1):未确定

4.      熔点(ºC):未确定

5.      沸点(ºC,常压):未确定

6.      沸点(ºC,8mm):未确定

7.      折射率:未确定

8.      闪点(ºF):85

9.      比旋光度(º):未确定

10.   自燃点或引燃温度(ºC):未确定

11.   蒸气压(kPa,25ºC):未确定

12.   饱和蒸气压(kPa,60ºC):未确定

13.   燃烧热(KJ/mol):未确定

14.   临界温度(ºC):未确定

15.   临界压力(KPa):未确定

16.   油水(辛醇/水)分配系数的对数值:未确定

17.   爆炸上限(%,V/V):未确定

18.   爆炸下限(%,V/V):未确定

19.   溶解性:微溶于水,溶于热水,不溶于醇。

醋酸铬 安全信息

危险类别码:
R36/37/38
安全说明:
S26-S36/37/39

醋酸铬 毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AG2975000
CHEMICAL NAME :
Acetic acid, chromium(3+) salt
CAS REGISTRY NUMBER :
1066-30-4
LAST UPDATED :
199712
DATA ITEMS CITED :
27
MOLECULAR FORMULA :
C6-H9-O6.Cr
MOLECULAR WEIGHT :
229.15
WISWESSER LINE NOTATION :
OV1 3 &-CR-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2290 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1604 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Amphibian - frog
DOSE/DURATION :
6185 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Implant
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1000 mg/kg/56W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

MUTATION DATA

TYPE OF TEST :
Mutation in mammalian somatic cells
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
200 umol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 117,279,1983 *** REVIEWS *** ACGIH TLV-TWA 0.5 mg(Cr)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-Not classifiable as a human carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Human Inadequate Evidence IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,165,1987 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 49,49,1990 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 23,205,1980 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 49,49,1990 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 49,49,1990 TOXICOLOGY REVIEW 85DHAX "Medical and Biologic Effects of Environmental Pollutants Series," Washington, DC, National Academy of Sciences, 1972-77 Volume(issue)/page/year: Cr,22,1974 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 1 mg(Cr)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,35,1971 OSHA PEL (Gen Indu):8H TWA 0.5 mg(Cr)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.5 mg(Cr)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.5 mg(Cr)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.5 mg(Cr)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84289 No. of Facilities: 28 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 168 (estimated)
毒理学数据:

1、急性毒性:兔子静脉注射LDLo:1604mg/kg

小鼠静脉注射LCLo:2290mg/kg

醋酸铬 MSDS


Section 1: Product Identification
   Chemical Name:       Chromium (III) acetate solution, 11.2-11.8% Cr    
   CAS Registry Number:       1066-30-4    
   Formula:       Cr(OOCCH3)3    
   EINECS Number:       none    
   Chemical Family:       metal acetate salt    
   Synonym:       Chromic acetate (III), Chromium triacetate, Acetic acid, chromium (III) salt    

Section 2: Composition and Information on Ingredients
   Ingredient       CAS Number       Percent       ACGIH (TWA)       OSHA (PEL)    
   Title Compound       1066-30-4       50%       0.5mg/m3       0.5mg/m3    
   water       7732-18-5       50%       no data       no data    

Section 3: Hazards Identification
   Emergency Overview:       Irritating to eyes and skin. May be harmful if swallowed. Possible risk of irreversible effects.    
   Primary Routes of Exposure:       Ingestion, eyes, inhalation    
   Eye Contact:       Causes slight to mild irritation of the eyes.    
   Skin Contact:       Causes slight to mild irritation of the skin.    
   Inhalation:       Material is an aqueous solution. Inhalation is not applicable.    
   Mae harmful if swallowed. Ingestion may cause gastrointestinal distress, burning of throat, dizziness and
   Ingestion:
   weakness.
   Acute Health Affects:       Irritating to skin, eyes and respiratory tract. May be harmful if swallowed.    
   Chronic Health Affects:       Possible risk of irreversible effects.    
   NTP:       Yes    
   IARC:       Yes    
   OSHA:       No    

SECTION 4: First Aid Measures
   Immediately flush the eyes with copious amounts of water for at least 10-15 minutes. A victim may need
   Eye Exposure:
   assistance in keeping their eye lids open. Get immediate medical attention.
   Wash the affected area with water. Remove contaminated clothes if necessary. Seek medical assistance if
   Skin Exposure:
   irritation persists.
   Remove the victim to fresh air. Closely monitor the victim for signs of respiratory problems, such as difficulty
   Inhalation:
   in breathing, coughing, wheezing, or pain. In such cases seek immediate medical assistance.
   Seek medical attention immediately. Keep the victim calm. Give the victim water (only if conscious). Induce
   Ingestion:
   vomiting only if directed by medical personnel.

SECTION 5: Fire Fighting Measures
   Flash Point:       none    
   Autoignition Temperature:       none    
   Explosion Limits:       none    
   Extinguishing Medium:       carbon dioxide, dry powder or foam    
   If involved in a fire, fire fighters should be equipped with a NIOSH approved positive pressure self-contained
   Special Fire Fighting Procedures:
   breathing apparatus and full protective clothing.
   Hazardous Combustion and       If involved in a fire this material may emit toxic organic fumes.    
   Decomposion Products:
   Unusual Fire or Explosion Hazards: No unusual fire or explosion hazards.

SECTION 6: Accidental Release Measures
   Spill and Leak Procedures:       Small spills can be absorbed in vermiculite or other suitable adsorbent.    

SECTION 7: Handling and Storage
   Handling and Storage:       Store in a tightly sealed container.    

SECTION 8: Exposure Controls and Personal Protection
   Eye Protection:       Always wear approved safety glasses when handling a chemical substance in the laboratory.    
   Skin Protection:       Wear protective clothing and gloves.    
   Ventilation:       If possible, handle the material in an efficient fume hood.    
   Respirator:       No respirator required.    
   Ventilation:       If possible, handle the material in an efficient fume hood.    
   Additional Protection:       No additional protection required.    

SECTION 9: Physical and Chemical Properties
   Color and Form:       liq.    
   Molecular Weight:       229.13    
   Melting Point:       no data    
   Boiling Point:       no data    
   Vapor Pressure:       no data    
   Specific Gravity:       1.28    
   Odor:       none    
   Solubility in Water:       material is an aqueous sol.    

SECTION 10: Stability and Reactivity
   Stability:       air and moisture stable liquid    
   Hazardous Polymerization:       no hazardous polymerization    
   Conditions to Avoid:       none    
   Incompatibility:       none    
   Decomposition Products:       Carbon dioxide, carbon monoxide, organic vapors, and metal oxides    

SECTION 11: Toxicological Information
   Intravenous (mouse); LDLo: 2290 mg/kg. Intravenous (rabbit); LDLo:1604 mg/kg. Intravenous (frog); LDLo:
   6185 mg/kg. Implant (rat); TDLo: 1000 mg/kg/56W-I. Bacteria-Escherichia coli; Mutation in microorganisms: 16
   RTECS Data:       mmol/L. Bacteria-Escheichia coli; DNA repair: 93 ug/well. Bacteria-Bacillus subtilis; DNA repair: 160 mmol/L.    
   Human Leukocyte; Cytogenetic analysis: 16 umol/L. Hamster Ovary; Cytogenetic analysis: 150 mg/L. Hamster
   Ovary; Mutation in mammalian somatic cells: 200 umol/L.
   Carcinogenic Effects:       No data available    
   Mutagenic Effects:       Possible mutagen    
   Tetratogenic Effects:       No data available    

SECTION 12: Ecological Information
   Ecological Information:       No information available    

SECTION 13: Disposal Considerations
   Disposal:       Dispose of according to local, state and federal regulations.    

SECTION 14: Transportation
   Shipping Name (CFR):       Non-hazardous    
   Hazard Class (CFR):       NA    
   Additional Hazard Class (CFR):       NA    
   Packaging Group (CFR):       NA    
   UN ID Number (CFR):       NA    
   Shipping Name (IATA):       Non-hazardous    
   Hazard Class (IATA):       NA    
   Additional Hazard Class (IATA):       NA    
   Packaging Group (IATA):       NA    
   UN ID Number (IATA):       NA    

SECTION 15: Regulatory Information
   TSCA:       Listed in the TSCA inventory    
   SARA (Title 313):       Title compound see Category Code N090 for reporting.    
   Second Ingredient:       none    


SECTION 16 - ADDITIONAL INFORMATION
N/A

醋酸铬 分子结构与计算化学数据

分子结构数据

1、摩尔折射率:无可用的

2、摩尔体积(cm3/mol):无可用的

3、等张比容(90.2K):无可用的

4、表面张力(dyne/cm):无可用的

5、介电常数:无可用的

6、极化率(10-24cm3):无可用的

7、单一同位素质量:228.980425 Da

8、标称质量:229 Da

9、平均质量:229.1282 Da

计算化学数据

1.疏水参数计算参考值(XlogP):无

2.氢键供体数量:0

3.氢键受体数量:6

4.可旋转化学键数量:0

5.互变异构体数量:无

6.拓扑分子极性表面积120

7.重原子数量:13

8.表面电荷:0

9.复杂度:25.5

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:4

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