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间型霉素B 基本信息
- 中文名称：
- 间型霉素B
- 中文别名：
- 间型霉素B
- 英文名称：
- Formycin B
- 英文别名：
- formycin B;
FORMYCIN B;
LAURUSIN;
D-Ribitol, 1,4-anhydro-1-C-(6,7-dihydro-7-oxo-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-, (S)-;
OHYAMYCIN
- CAS No.：
- 13877-76-4
- 分 子 式：
-
C10H12N4O5
- 分 子 量：
- 268.23
- 精确分子量：
- 268.08100
- PSA：
- 144.35000
- InChI：
- The Key: MTCJZZBQNCXKAP-KSYZLYKTSA-N
- 危险品标志：
-
- 风险术语：
-
- 安全术语：
-
- 分子结构式：
-
- SDS：
- 查看
间型霉素B 物化性质
- 密度：
- 2.18g/cm3
- 沸点：
- 683.2ºC at 760mmHg
- 闪点：
- 367ºC
- 折射率：
- 1.921
- 蒸汽压：
- 1.34E-19mmHg at 25°C
间型霉素B 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UR0800000
- CHEMICAL NAME :
- 7H-Pyrazolo(4,3-d)pyrimidin-7-one,
1,4-dihydro-3-beta-D-ribofuranosyl-
- CAS REGISTRY NUMBER :
- 13877-76-4
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C10-H12-N4-O5
- MOLECULAR WEIGHT :
- 268.26
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- >50 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Parenteral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4 gm/kg/10D-I
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain
Related to Chronic Data - death
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 10 umol/L
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year:
30,2651,1981
