甲硝唑
中文名称: 甲硝唑
中文同义词: 2-甲基-5-硝基-1H-咪唑-1-乙醇；甲硝哒唑；灭滴灵；甲硝唑；2-甲基-5-硝基咪唑-1-乙醇；1-(2-羟乙基)-2-甲基-5-硝基咪唑；硝基羟乙唑；甲硝哒唑/甲硝唑
英文名称: Metronidazole
英文同义词: 1-(2-Hydroxy-1-ethyl)-2-methyl-5-nitroimidazole；1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole；1-(beta-Hydroxyethyl)-2-methyl-5-nitroimidazole；1-(beta-Oxyethyl)-2-methyl-5-nitroimidazole；1H-Imidazole-1-ethanol, 2-methyl-5-nitro-；1H-Imidazole-1-ethanol,2-methyl-5-nitro-；1-Hydroxyethyl-2-methyl-5-nitroimidazole；2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethanol
CAS号: 443-48-1
分子式: C6H9N3O3
分子量: 171.15
EINECS号: 207-136-1
熔点 159-161 °C(lit.)
储存条件 2-8°C
溶解度 acetic acid: 0.1 M, clear, faintly yellow
form crystalline
水溶解性 ＜0.1 g/100 mL at 20 oC
Merck 6157
稳定性 Stable. Incompatible with strong oxidizing agents.
NIST化学物质信息 Metronidazole(443-48-1)
EPA化学物质信息 1H-Imidazole-1-ethanol, 2-methyl-5-nitro-(443-48-1)
化学性质 白色或乳白色结晶性粉末。熔点158-160。溶于热水，略溶于乙醇，微溶于水或氯仿，极微溶于乙醚。味苦而略咸。
用途 该品于1959年起用于治疗阴道滴虫病，1970年开始用于肠道内、外阿米巴病，其疗效高，毒性低，应用广。对动物实验有致突变和致畸作用。
Metronidazole
Synonyms: 2-Methyl-5-nitroimidazole-1-ethanol
CAS: 443-48-1
EINECS: 207-136-1
Assay: 99.0％~101.0％.
Standard: BP2010/ EP/USP
Packing: 25Kg/cardboard drum
MF: C6H9N3O3
MW: 171.15
Character: White crystalline powder. with a slight odor. Bitter and saline taste. pH (saturated aqueous solution) about 6.5. Mp159-161℃. Insoluble in water, acetic acid: 0.1 M, clear, faintly yellow.
Usage: Used as an antibacterial in the treatment of rosacea. Antiprotozoal (trichomonas). A potential human carcinogen.
For most anaerobic bacteria with strong antibacterial effect. For the treatment of amoebiasis, trichomoniasis and anaerobic infections. The product in 1959 for the treatment of vaginal trichomoniasis, 1970 for the intestine, outside amoebiasis, its high effic
