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112809-51-5
Letrozole

  • Product Name: Letrozole
  • Cas No: 112809-51-5
  • Formula: C17H11N5
  • EINECS: 675-034-8
  • Appearance: white to off-whitecrystalline powder
  • synonyms: 4,4'-(1H-1,2,4-Triazol-1-ylmethylene)bisbenzonitrile
customization: Available

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Description

Letrozole, a third-generation aromatase inhibitor preventing estrogen synthesis from testosterone, is used as an adjuvant therapy in estrogen receptor-positive breast cancer patients. Aromatase inhibitors, such as letrozole, are usually prescribed as daily oral treatment over 3 to 5 years. It is used in the treatment of PCOS for ovulation induction and in patients with peripheral precocious puberty caused by McCune-Albright syndrome. Aromatase inhibitors block the conversion of androgens to estrogens, delay bone age progression, allow for normal masculinization and stimulate longitudinal bone growth through androgen receptor action on the growth plate, thereby improving the height of patients. Studies conducted on boys with constitutional growth delay, idiopathic short stature (ISS), and GH deficiency have shown that the use of AI alone or in combination with rhGH may increase final adult height by by delaying epiphyseal fusion. Use of letrozole alone in girls may lead to an increase in gonadotropins. Therefore, GnRHa should be used simultaneously to suppress gonadotropins.

There are many suppliers of Letrozole on the LookChem platform, such as Xi'an Xszo Chem Co., Ltd., Shaanxi New nine Material Technology Co., Ltd., Shanghai SE Pharm Co., Ltd. Through the form on the right, you can choose to send an inquiry to your intended factory. We recommend that you clearly describe your purchase requirements, for example: Letrozole CAS number 112809-51-5 with a purity of over 98% that needs to be transported to Los Angeles, USA.

Here are some small packages of Letrozole price information you can contact us to purchase, if you need to purchase Letrozole in bulk, please send an inquiry message to get the latest prices and offers.

Name CAS Size Price(USD)
MACKLIN 112809-51-5 100.00g 385.97
MACKLIN 112809-51-5 25.00g 131.34
MACKLIN 112809-51-5 5.00g 41.19
MACKLIN 112809-51-5 1.00g 13.88
Acmec 112809-51-5 100.00mg 28.06
Boer 112809-51-5 25.00g 130.45
Boer 112809-51-5 100.00g 374.48
Boer 112809-51-5 1.00g 13.73
Boer 112809-51-5 5.00g 40.45
MAYA 112809-51-5 1.00G 8.96
MAYA 112809-51-5 5.00G 35.82
Psaitong 112809-51-5 100.00g 380.60
Psaitong 112809-51-5 5.00g 41.79
Psaitong 112809-51-5 25.00g 126.87
Psaitong 112809-51-5 1.00g 12.69