美西律

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物化性质
安全信息
毒理性
海关数据
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美西律基本信息

中文名称：: 美西律

中文别名：: 美西律;
1-(2,6-二甲基苯氧基)-2-丙胺;
2-溴-4'-碘苯乙酮;
1-Bromo-3-methoxy-2-methylbenzene;
Propionanilide,2-amino-4'-nitro-, monohydrochloride, L- (8CI);
L-Alanine-4-nitroanilidehydrochloride;
L-Alanine-p-nitroanilide hydrochloride;
(S)-2-amino-N-(4-nitrophenyl)propionamide hydrochloride;
(-)-Corey lactone, 4-phenylbenzoate alcohol;
E,Z-9,12-十四碳烯-1-醇乙酸酯;
9,12-(E,Z)-十四碳烯-1-醇乙酸酯;
(反,顺)-9,12-十四碳烯-1-醇乙酸酯;
(Z9,E12)-十四碳烯-1-醇乙酸酯;
Diethyl p-toluene sulfonyl oxymethyl phosphonate;<

英文名称：: 2-Propanamine,1-(2,6-dimethylphenoxy)-

英文别名：: mexiletine;
Mexilitene;
Ritalmex;
Olzoron;
ko1173;
Cirumimeru;
MEXILITINE HCL;
1-(2,6-Dimethylphenoxy)-2-propanamine;
Toy;
Ko 1173Cl;
mexitil;
Katen

CAS No.：: 31828-71-4

分子式：: C₁₁H₁₇NO

分子量：: 179.26

精确分子量：: 179.13100

PSA：: 35.25000

EINECS：: 250-825-7

InChI：: InChI:1S/C11H17NO/c1-8-5-4-6-9(2)11(8)13-7-10(3)12/h4-6,10H,7,12H2,1-3H3

危险品标志：

风险术语：: R20/21/22

安全术语：: S36

分子结构式：

SDS：: 查看

美西律物化性质

密度：: 0.979 g/cm3
熔点：: 203-205ºC
沸点：: 271.5ºC at 760 mmHg
闪点：: 112.2ºC

美西律安全信息

包装等级：: III
风险类别：: 6.1(b)
海关代码：: 2922299090
危险类别码：: R20/21/22
安全说明：: S36
危险标志：: Xn: Harmful;

美西律毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KR9300000

CHEMICAL NAME :: Ethylamine, 1-methyl-2-(2,6-xylyloxy)-

CAS REGISTRY NUMBER :: 31828-71-4

LAST UPDATED :: 199703

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C11-H17-N-O

MOLECULAR WEIGHT :: 179.29

WISWESSER LINE NOTATION :: ZY1&1OR B1 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human

DOSE/DURATION :: 63 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis Gastrointestinal - nausea or vomiting

REFERENCE :: PMESAJ Postgraduate Medical Journal, Supplement. (Blackwell Scientific Pub. Ltd., POB 88, Oxford, UK) V.1- 1949- Volume(issue)/page/year: 53(Suppl 1),134,1977

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human - man

DOSE/DURATION :: 349 mg/kg/4D-I

TOXIC EFFECTS :: Blood - thrombocytopenia

REFERENCE :: AIMEAS Annals of Internal Medicine. (American College of Physicians, 4200 Pine St., Philadelphia, PA 19104) V.1- 1927- Volume(issue)/page/year: 100,162,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 41 mg/kg

TOXIC EFFECTS :: Toxic effects not yet reviewed

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #5116974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 320 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DECRDP Drugs under Experimental and Clinical Research. (Bioscience Ediprint, Blvd. James-Fazy 13, 1201 Geneva 1, Switzerland) V.1- 1977- Volume(issue)/page/year: 13,21,1987

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 114 mg/kg

TOXIC EFFECTS :: Cardiac - arrhythmias (including changes in conduction)

REFERENCE :: EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 21,370,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 23 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 41,1130,1991

美西律海关数据

中国海关编码：2922299090

概述：: 2922299090. 其他氨基(萘酚、酚)及醚、酯〔包括它们的盐, 但含有一种以上含氧基的除外〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素：: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
摘要/Summary：: 2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%