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基本信息
- 中文名称：
-
- 中文别名：
-
- 英文名称：
- 2-Propenamide,N-[2-[[3-(dimethylamino)propyl]thio]phenyl]-3-phenyl-, hydrochloride (1:1)
- 英文别名：
- CINANSERIN HYDROCHLORIDE;
maptc;
Cinnanserin;
sq10,643;
CINANSERIN;
DPTC HYDROCHLORIDE;
DPTC
- CAS No.：
- 54-84-2
- 分 子 式：
- C20H24N2OS.ClH
- 分 子 量：
- 376.98
- 精确分子量：
- 376.13800
- PSA：
- 57.64000
- 安全术语：
- Poison by intravenous route. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of SOx, NOx, and HCl.
- 分子结构式：
-
- SDS：
- 查看
物化性质
- 沸点：
- 519.5ºC at 760mmHg
- 闪点：
- 268ºC
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GD7478000
- CHEMICAL NAME :
- Cinnamanilide, 2'-((3-(dimethylamino)propyl)thio)-,
monohydrochloride
- CAS REGISTRY NUMBER :
- 54-84-2
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C20-H24-N2-O-S.Cl-H
- MOLECULAR WEIGHT :
- 376.98
- WISWESSER LINE NOTATION :
- 1N1&3SR BMV1U1R &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1500 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Behavioral - changes in motor activity (specific assay)
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 152,132,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 480 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Behavioral - changes in motor activity (specific assay)
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 152,132,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 35 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Behavioral - changes in motor activity (specific assay)
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 152,132,1964
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 8 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Behavioral - changes in motor activity (specific assay)
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 152,132,1964
