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- 6-甲基-alpha-(4-甲基-1-哌嗪基羰基)麦角灵-8-beta-丙腈
6-甲基-alpha-(4-甲基-1-哌嗪基羰基)麦角灵-8-beta-丙腈
6-甲基-alpha-(4-甲基-1-哌嗪基羰基)麦角灵-8-beta-丙腈 基本信息
- 中文名称：
- 6-甲基-alpha-(4-甲基-1-哌嗪基羰基)麦角灵-8-beta-丙腈
- 中文别名：
-
- 英文名称：
- Piperazine,1-[2-cyano-3-[(8b)-6-methylergolin-8-yl]-1-oxopropyl]-4-methyl-(9CI)
- 英文别名：
- 2-[[(6aR,9S)-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-yl]methyl]-3-(4-methylpiperazin-1-yl)-3-oxopropanenitrile;
Piperazine,1-[2-cyano-3-[(8b)-6-methylergolin-8-yl]-1-oxopropyl]-4-methyl-(9CI)
- CAS No.：
- 74627-31-9
- 分 子 式：
- C24H31N5O
- 分 子 量：
- 0
- 精确分子量：
- 405.25300
- PSA：
- 66.37000
- 分子结构式：
-
- SDS：
- 查看
6-甲基-alpha-(4-甲基-1-哌嗪基羰基)麦角灵-8-beta-丙腈 物化性质
- 密度：
- 1.204g/cm3
- 沸点：
- 641.9ºC at 760 mmHg
- 闪点：
- 342ºC
- 折射率：
- 1.615
6-甲基-alpha-(4-甲基-1-哌嗪基羰基)麦角灵-8-beta-丙腈 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KE6345210
- CHEMICAL NAME :
- Ergoline-8-beta-propionitrile,
6-methyl-alpha-(4-methyl-1-piperazinylcarbonyl)-
- CAS REGISTRY NUMBER :
- 74627-31-9
- LAST UPDATED :
- 199309
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C24-H31-N5-O
- MOLECULAR WEIGHT :
- 405.60
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Vascular - BP lowering not characterized in autonomic section
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 33,1094,1983
** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 16 mg/kg
- SEX/DURATION :
- female 5 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
number of implants per female; total number of implants per corpora lutea)
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 33,1094,1983
