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- [D-蛋氨酰2,脯氨酰5]-脑啡肽酰胺
[D-蛋氨酰2,脯氨酰5]-脑啡肽酰胺 基本信息
- 中文名称：
- [D-蛋氨酰2,脯氨酰5]-脑啡肽酰胺
- 中文别名：
- 1-[2-[[2-[[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carboxamide
- 英文名称：
- L-Prolinamide,L-tyrosyl-D-methionylglycyl-L-phenylalanyl- (9CI)
- 英文别名：
- 1-[2-[[2-[[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carboxamide;
H-Tyr-D-Met-Gly-Phe-Pro-NH2;
L-tyrosyl-D-methionyl-glycyl-L-phenylalanyl-L-proline amide;
Tyr-D-Met-Gly-Phe-Pro-NH2
- CAS No.：
- 63307-63-1
- 分 子 式：
- C30H40N6O6S
- 分 子 量：
- 612.7402
- 精确分子量：
- 612.27300
- PSA：
- 233.71000
- InChI：
- The Key: UIRWGVLTPPSGEN-NDBXHCKUSA-N
- 分子结构式：
-
- SDS：
- 查看
[D-蛋氨酰2,脯氨酰5]-脑啡肽酰胺 物化性质
- 密度：
- 1.31g/cm3
- 沸点：
- 1065ºC at 760 mmHg
- 闪点：
- 597.9ºC
- 折射率：
- 1.616
[D-蛋氨酰2,脯氨酰5]-脑啡肽酰胺 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TW3583000
- CHEMICAL NAME :
- L-Prolinamide,
L-tyrosyl-D-methionylglycyl-L-phenylalanyl-
- CAS REGISTRY NUMBER :
- 63307-63-1
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C30-H40-N6-O6-S
- MOLECULAR WEIGHT :
- 612.82
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 510 mg/kg
- TOXIC EFFECTS :
- Behavioral - rigidity (including catalepsy)
Behavioral - antipsychotic
Behavioral - alteration of classical conditioning
- REFERENCE :
- PJPPAA Polish Journal of Pharmacology and Pharmacy. (ARS Polona, POB 1001,
00-068 Warsaw 1, Poland) V.25- 1973- Volume(issue)/page/year:
39,641,1987
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 118 mg/kg
- TOXIC EFFECTS :
- Behavioral - rigidity (including catalepsy)
Behavioral - antipsychotic
Behavioral - alteration of classical conditioning
- REFERENCE :
- PJPPAA Polish Journal of Pharmacology and Pharmacy. (ARS Polona, POB 1001,
00-068 Warsaw 1, Poland) V.25- 1973- Volume(issue)/page/year:
39,641,1987
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1700 mg/kg
- TOXIC EFFECTS :
- Behavioral - rigidity (including catalepsy)
Behavioral - antipsychotic
Behavioral - alteration of classical conditioning
- REFERENCE :
- PJPPAA Polish Journal of Pharmacology and Pharmacy. (ARS Polona, POB 1001,
00-068 Warsaw 1, Poland) V.25- 1973- Volume(issue)/page/year:
39,641,1987
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 278 mg/kg
- TOXIC EFFECTS :
- Behavioral - rigidity (including catalepsy)
Behavioral - antipsychotic
Behavioral - alteration of classical conditioning
- REFERENCE :
- PJPPAA Polish Journal of Pharmacology and Pharmacy. (ARS Polona, POB 1001,
00-068 Warsaw 1, Poland) V.25- 1973- Volume(issue)/page/year:
39,641,1987
