二丙二醇单甲醚

外观与性状：

无色液体带有温和令人愉快的气味

密度：

0.954 g/mL at 20 °C(lit.)

熔点：

-80°C

沸点：

90-91 °C12 mm Hg(lit.)

闪点：

166 °F

折射率：

n20/D 1.422

存储条件/存储方法：

包装完整、轻装轻卸,库房通风、远离明火、高温、与氧化剂分开存放

其它信息：

1.        性状：无色透明粘稠液体

2.         密度（g/mL,25/25℃）：0.954

3.         相对蒸汽密度（g/mL,空气=1）：5.11

4.         熔点（ºC）：-80

5.         沸点（ºC,常压）：190

6.         沸点（ºC,1.6KPa）：90-91

7.         折射率（25ºC）：1.419

8.         闪点（ºC,开口）：85

9.         黏度（mPa·s,25ºC）：3.33

10.      蒸气压（KPa,25ºC）：0.05

11.      溶解性：与水混溶。能溶解油脂、橡胶、天然树脂乙基纤维素、硝酸纤维素、聚乙酸乙烯酯、聚乙烯醇缩丁醛、醇酸树脂、酚醛树脂、尿素树脂等。

海关代码：

29094919

WGK_Germany：

1
德国有关水污染物质的分类清单

安全说明：

S23-S24/25

RTECS号：

JM1575000

安全标志：

S23:不要吸入蒸汽。
S24/25:防止皮肤和眼睛接触。

CHEMICAL IDENTIFICATION

RTECS NUMBER :

JM1575000

CHEMICAL NAME :

Dipropylene glycol, monomethyl ether

CAS REGISTRY NUMBER :

34590-94-8

LAST UPDATED :

199712

DATA ITEMS CITED :

33

MOLECULAR FORMULA :

C7-H16-O3

MOLECULAR WEIGHT :

148.23

WISWESSER LINE NOTATION :

QY1&1O1Y1&O1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration into the eye

SPECIES OBSERVED :

Human

REFERENCE :

JTOTDO Journal of Toxicology, Cutaneous and Ocular Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1982- Volume(issue)/page/year: 2,229,1983/1984

TYPE OF TEST :

Open irritation test

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

REFERENCE :

UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 11/15/1971

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration into the eye

SPECIES OBSERVED :

Rodent - rabbit

REFERENCE :

85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,633,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

5400 uL/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 9,509,1954

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Mammal - dog

DOSE/DURATION :

7500 mg/kg

TOXIC EFFECTS :

Lungs, Thorax, or Respiration - other changes

REFERENCE :

JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 102,79,1951

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

10 mL/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

650 mL/kg/13W-I

REFERENCE :

AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 9,509,1954 *** REVIEWS *** ACGIH TLV-STEL 909 mg/m3 (150 ppm) (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 606 mg/m3 (100 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 100 ppm (600 mg/m3) (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,96,1971 OSHA PEL (Gen Indu):8H TWA 100 ppm (600 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 100 ppm (600 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 100 ppm (600 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 100 ppm (600 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 100 ppm (600 mg/m3);STEL 150 ppm;Skin JAN 1993 OEL-AUSTRIA:TWA 50 ppm (300 mg/m3) JAN 1993 OEL-BELGIUM:TWA 100 ppm (606 mg/m3);STEL 150 ppm;Skin JAN 1993 OEL-DENMARK:TWA 100 ppm (600 mg/m3);Skin JAN 1993 OEL-FINLAND:TWA 100 ppm (600 mg/m3);STEL 150 ppm;Skin JAN 1993 OEL-FRANCE:TWA 100 ppm (600 mg/m3) JAN 1993 OEL-GERMANY:TWA 50 ppm (300 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 50 ppm (300 mg/m3) JAN 1993 OEL-THE PHILIPPINES:TWA 100 ppm (600 mg/m3);Skin JAN 1993 OEL-SWITZERLAND:TWA 50 ppm (300 mg/m3);STEL 100 ppm (600 mg/m3) JAN 1993 OEL-TURKEY:TWA 300 ppm (600 mg/m3);Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO THE CHEMICAL-air:10H TWA 100 ppm (Sk);STEL 150 ppm (Sk) REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84537 No. of Facilities: 5594 (estimated) No. of Industries: 66 No. of Occupations: 55 No. of Employees: 52536 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84537 No. of Facilities: 15846 (estimated) No. of Industries: 123 No. of Occupations: 89 No. of Employees: 210740 (estimated) No. of Female Employees: 21792 (estimated)

毒理学数据：

1、   皮肤、眼睛刺激毒性：人经眼Draize标准实验：8mg

                                                 兔子皮肤开放式刺激实验：500mg

                                                 兔子经眼Draize标准实验：500mg/24H

2、   急性毒性：大鼠经口LD50：5400mL/kg；狗经口LD50：7500mg/kg

                             兔子皮肤LD50：10mL/kg

3、   其他多剂量毒性：兔子皮肤TDLo：650mg/kg/13W-I

4、属低毒类，雄大鼠经口LD50为5.50mL/kg，雌大鼠经口LD50为5.45mL/kg。动物中毒表现以中枢神经抑制为主，死于呼吸衰竭。

 

分子结构数据

1、   摩尔折射率：39.50

2、   摩尔体积（cm³/mol）：154.3                

3、   等张比容（90.2K）：366.7

4、   表面张力（dyne/cm）：31.8

5、   介电常数：

6、   偶极距（10^-24cm³）：

7、   极化率：15.66

计算化学数据

1、   疏水参数计算参考值（XlogP）：0.7

2、   氢键供体数量：1

3、   氢键受体数量：3

4、   可旋转化学键数量：6

5、   互变异构体数量：

6、   拓扑分子极性表面积（TPSA）：38.7

7、   重原子数量：10

8、   表面电荷：0

9、   复杂度：65.9

10、同位素原子数量：0

11、确定原子立构中心数量：0

12、不确定原子立构中心数量：1

13、确定化学键立构中心数量：0

14、不确定化学键立构中心数量：0

15、共价键单元数量：1

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  二丙二醇单甲醚红外图谱(IR1)