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- 2-[4-[3-[2-(三氟甲基)吩噻嗪-10-基]丙基]哌嗪-1-基]乙基庚酸酯
2-[4-[3-[2-(三氟甲基)吩噻嗪-10-基]丙基]哌嗪-1-基]乙基庚酸酯
2-[4-[3-[2-(三氟甲基)吩噻嗪-10-基]丙基]哌嗪-1-基]乙基庚酸酯 基本信息
- 中文名称：
- 2-[4-[3-[2-(三氟甲基)吩噻嗪-10-基]丙基]哌嗪-1-基]乙基庚酸酯
- 中文别名：
-
- 英文名称：
- Heptanoic acid,2-[4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazinyl]ethylester
- 英文别名：
- 2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethyl heptanoate;
Fluphenazine enantate;
2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethyl heptanoate;
Fluphenazinenanthat;
Fluphenanzin-aenanthat;
2-[4-[3-[2-(Trifluoromethyl)phenothiazin-10-yl]propyl]-1-piperazinyl]ethyl heptanoate;
Fluphenazin-aenanthsaeureester;
4-<3-<2-Trifluormethyl-phenothiazinyl-(10)>-propyl>-1-(2-hydroxy-ethyl)-piperazin-heptanoat;
1-heptanoyloxy-2-{4-[3-(2-trifluoromethyl-phenothiazin-10-yl)-propyl]-piperazin-1-yl}-ethane;
Moditen-retard;
Prolixin Enanthate;
fluphenazine enanthate;
fluphenazine O-enantate;
Eutimox;
EINECS 220-385-0
- CAS No.：
- 2746-81-8
- 分 子 式：
- C29H38F3N3O2S
- 分 子 量：
- 549.76
- 精确分子量：
- 549.26400
- PSA：
- 61.32000
- EINECS：
- 220-385-0
- InChI：
- The Key: LRWSFOSWNAQHHW-UHFFFAOYSA-N
- 安全术语：
- Poison by intravenous, intramuscular, intraperitoneal, and subcutaneous routes. Human systemic effects by subcutaneous route: muscle weakness; by intramuscular route: musculo-skeletal changes. When heated to decomposition it emits very toxic fumes of F−, SOx, and NOx.
- 分子结构式：
-
- SDS：
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2-[4-[3-[2-(三氟甲基)吩噻嗪-10-基]丙基]哌嗪-1-基]乙基庚酸酯 物化性质
- 密度：
- 1.181g/cm3
- 沸点：
- 629.4ºC at 760mmHg
- 闪点：
- 334.4ºC
- 折射率：
- 1.544
- 蒸汽压：
- 9.41E-16mmHg at 25°C
2-[4-[3-[2-(三氟甲基)吩噻嗪-10-基]丙基]哌嗪-1-基]乙基庚酸酯 安全信息
2-[4-[3-[2-(三氟甲基)吩噻嗪-10-基]丙基]哌嗪-1-基]乙基庚酸酯 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MJ2450000
- CHEMICAL NAME :
- Heptanoic acid,
2-(4-(3-(2-(trifluoromethyl)phenothiazin-10-yl)propyl
)- 1-piperazinyl)ethyl ester
- CAS REGISTRY NUMBER :
- 2746-81-8
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C29-H38-F3-N3-O2-S
- MOLECULAR WEIGHT :
- 549.76
- WISWESSER LINE NOTATION :
- T C666 BN ISJ EXFFF B3- AT6N DNTJ D2OV6
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 357 ug/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness
- REFERENCE :
- AJPSAO American Journal of Psychiatry. (American Psychiatric Assoc.,
Circulation Dept., 1400 K St., NW, Washington, DC 20005) V.78- 1921-
Volume(issue)/page/year: 119,779,1963
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 1633 ug/kg
- TOXIC EFFECTS :
- Musculoskeletal - other changes
- REFERENCE :
- BMJOAE British Medical Journal. (British Medical Assoc., BMA House,
Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year:
2,1071,1966
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,701,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,701,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 56 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010)
Volume(issue)/page/year: NX#03337
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 17200 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,701,1982
*** REVIEWS ***
TOXICOLOGY REVIEW
ABPYBL Advances in Biochemical Psychopharmacology. (Raven Press, 1185 Ave.
of the Americas, New York, NY 10036) V.1- 1969- Volume(issue)/page/year:
9,301,1974
