甘露醇-1,6-二磺酸

密度：

1.635g/cm3

沸点：

721.3ºC at 760 mmHg

闪点：

390ºC

折射率：

1.553

蒸汽压：

5.01E-24mmHg at 25°C

存储条件/存储方法：

库房通风低温干燥,与食品原料分开存放

稳定性相关：

1.中毒，可燃，受热分解有毒硫氧化物烟雾。

海关代码：

2905499000

CHEMICAL IDENTIFICATION

RTECS NUMBER :

OP2975000

CHEMICAL NAME :

Mannitol, 1,6-dimethanesulfonate, D-

CAS REGISTRY NUMBER :

1187-00-4

LAST UPDATED :

199707

DATA ITEMS CITED :

12

MOLECULAR FORMULA :

C8-H18-O10-S2

MOLECULAR WEIGHT :

338.38

WISWESSER LINE NOTATION :

WS1&O1YQYQYQYQ1OSW1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

2 gm/kg

TOXIC EFFECTS :

Blood - normocytic anemia Blood - thrombocytopenia

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

6 gm/kg

TOXIC EFFECTS :

Tumorigenic - protects against induction of experimental tumors

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

2500 mg/kg

TOXIC EFFECTS :

Tumorigenic - protects against induction of experimental tumors

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Mammal - dog

DOSE/DURATION :

135 mg/kg

TOXIC EFFECTS :

Blood - leukopenia Blood - agranulocytosis Blood - other changes

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Primate - monkey

DOSE/DURATION :

135 mg/kg

TOXIC EFFECTS :

Blood - leukopenia Blood - agranulocytosis Blood - other changes

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

1000 mg/kg/4W

TOXIC EFFECTS :

Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors

TYPE OF TEST :

Specific locus test

TYPE OF TEST :

Cytogenetic analysis

TYPE OF TEST :

Sex chromosome loss and nondisjunction

TYPE OF TEST :

Sex chromosome loss and nondisjunction

MUTATION DATA

TYPE OF TEST :

DNA inhibition

TEST SYSTEM :

Rodent - rabbit Bone marrow

DOSE/DURATION :

1700 umol/L

REFERENCE :

BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 25,1705,1976

毒理学数据：

腹腔-大鼠 LA50: 2000 毫克/公斤; 口服-小鼠 LD50: 6000 毫克/公斤

中国海关编码：2905499000

概述：

2905499000 其他多元醇。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:5.5%。普通关税:30.0%

申报要素：

品名, 成分含量, 用途, 包装

摘要/Summary：

2905499000 other polyhydric alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

分子结构数据

1、  摩尔折射率：66.25

2、  摩尔体积（cm³/mol）：206.9

3、  等张比容（90.2K）：612.5

4、  表面张力（dyne/cm）：76.8

5、  极化率（10-24cm3）：26.26