产品供求
蜂斗菜碱 基本信息
- 中文名称：
- 蜂斗菜碱
- 中文别名：
-
- 英文名称：
- Spiro[2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-ene-4,2'-oxirane]-3,8,17-trione,7-hydroxy-3',6,7,14-tetramethyl-, (1R,2'R,3'R,6R,7R)-
- 英文别名：
- Petasitenine (neutral);
(15R,20R)-15,20-Epoxy-15,20-dihydro-12-hydroxy-4-methyl-4,8-secosenecionan-8,11,16-trione;
Otosenin,Othosenin;
Petasitenine;
PETASITINENE
- CAS No.：
- 60102-37-6
- 分 子 式：
- C19H27NO7
- 分 子 量：
- 381.47
- 精确分子量：
- 381.17900
- PSA：
- 105.67000
- InChI：
- The Key: CZQLULNMKQAIQL-GZSSMBGUSA-N
- 安全术语：
- Questionable carcinogen with experimental carcinogenic data. Mutation data reported. Used as a food and herbal remedy. When heated to decomposition it emits toxic fumes of NOx.
- 分子结构式：
-
- SDS：
- 查看
蜂斗菜碱 物化性质
- 密度：
- 1.29g/cm3
- 沸点：
- 614.7ºC at 760 mmHg
- 闪点：
- 325.6ºC
- 折射率：
- 1.557
蜂斗菜碱 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SE5085000
- CHEMICAL NAME :
- Petasitenine
- CAS REGISTRY NUMBER :
- 60102-37-6
- LAST UPDATED :
- 199510
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C19-H27-N-O7
- MOLECULAR WEIGHT :
- 381.47
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 921 mg/kg/13W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria
Liver - tumors
MUTATION DATA
- TYPE OF TEST :
- Unscheduled DNA synthesis
- TEST SYSTEM :
- Rodent - rat Liver
- DOSE/DURATION :
- 2 umol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
45,3125,1985
*** REVIEWS ***
IARC Cancer Review:Animal Limited Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 31,207,1983
IARC Cancer Review:Human No Adequate Data
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 31,207,1983
IARC Cancer Review:Group 3
IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49
Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year:
7,56,1987
TOXICOLOGY REVIEW
PPTCBY Proceedings of the International Symposium of the Princess Takamatsu
Cancer Research Fund. (Japan Scientific Soc. Press, 6-2-10 Hongo, Bunkyo-ku,
Tokyo 113, Japan) 1st- 1971- Volume(issue)/page/year: 9,79,1979
