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基本信息
- 中文名称：
-
- 中文别名：
-
- 英文名称：
- 1-Propanone,3-(1-piperidinyl)-1-(4-propoxyphenyl)-, hydrochloride (1:1)
- 英文别名：
- Propiocaine Hydrochloride;
3-piperidin-1-yl-1-(4-propoxyphenyl)propan-1-one,hydrochloride
- CAS No.：
- 1155-49-3
- 分 子 式：
- C17H25NO2.ClH
- 分 子 量：
- 311.89
- 精确分子量：
- 311.16500
- PSA：
- 29.54000
- InChI：
- The Key: SLARELGEGUUVPI-UHFFFAOYSA-N
- 安全术语：
- Poison by ingestion, subcutaneous, and intravenous routes. When heated to decomposition it emits very toxic fumes of HCl and NOx.
- 分子结构式：
-
- SDS：
- 查看
物化性质
- 密度：
- 1.027g/cm3
- 沸点：
- 411.4ºC at 760mmHg
- 闪点：
- 202.6ºC
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UH4420000
- CHEMICAL NAME :
- Propiophenone, 3-piperidino-4'-propoxy-,
hydrochloride
- CAS REGISTRY NUMBER :
- 1155-49-3
- LAST UPDATED :
- 199009
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C17-H25-N-O2.Cl-H
- MOLECULAR WEIGHT :
- 311.89
- WISWESSER LINE NOTATION :
- T6NTJ A2VR DO3 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 125 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18,
Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year:
31,21,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 57 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 5,559,1955
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 15 mg/kg
- TOXIC EFFECTS :
- Behavioral - ataxia
Behavioral - muscle contraction or spasticity
Behavioral - irritability
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 115,419,1955
