二盐酸珠氯噻醇

  • 基本信息
  • 毒理性

二盐酸珠氯噻醇 基本信息

中文名称:
二盐酸珠氯噻醇 
中文别名:
二盐酸珠氯噻醇;
珠氯噻醇盐酸盐;
高抗素;
(3beta)-cholest-5-en-3-yl propanoate;
Cholesteryl propionate;
[4-[(4-diethylaminophenyl)-phenyl-methylene]-1-cyclohexa-2,5-dienylidene]-diethyl-ammonium,sulfuric acid;
Brilliant green;
Basic Viloet14;
Fuchsin basic;
Basic Violet 14;
bromophthal;
Tetrabromophthalic anhydride;
Phosphorsaeure-bis-(p-nitro-phenylester) [German];
p-Nitrophenyl monohydrogen phosphate;
Bis(4-nitrophenyl) hydrogen phosphate;
Phosphoric acid, bis(p-ni 
英文名称:
1-Piperazineethanol,4-[3-(2-chloro-9H-thioxanthen-9-ylidene)propyl]-, hydrochloride (1:2)
英文别名:
1-Piperazineethanol,4-[3-(2-chloro-9H-thioxanthen-9-ylidene)propyl]-, hydrochloride (1:2);
CLOPENTHIXOL DIHYDROCHLORIDE;
2-(4-(3-(2-Chloro-9H-thioxanthen-9-ylidene)propyl)piperazin-1-yl)ethanol dihydrochloride;
2-[4-[3-(2-Chlorothioxanthen-9-Ylidene)Propyl]Piperazin-1-Yl]Ethanol Dihydrochloride;
4-[3-(2-chloro-9H-thioxanthen-9-ylidene)propyl]piperazine-1-ethanol dihydrochloride 
CAS No.:
633-59-0
分 子 式:
C22H25ClN2OS.2ClH
分 子 量:
473.92
精确分子量:
436.11400
PSA:
52.01000
EINECS:
211-194-3
InChI:
InChI=1/C22H25ClN2OS.2ClH/c23-17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)27-22)5-3-9-24-10-12-25(13-11-24)14-15-26;;/h1-2,4-8,16,26H,3,9-15H2;2*1H
安全术语:
Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of SOx, NOx, and Cl−.
分子结构式:
SDS:
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二盐酸珠氯噻醇 毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TL8575000
CHEMICAL NAME :
1-Piperazineethanol, 4-(3-(2-chlorothioxanthen-9-ylidene)propyl)-, dihydrochloride
CAS REGISTRY NUMBER :
633-59-0
LAST UPDATED :
199507
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C22-H25-Cl-N2-O-S.2Cl-H
MOLECULAR WEIGHT :
473.92
WISWESSER LINE NOTATION :
T C666 BS IYJ EG IU3- AT6N DNTJ D2Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
660 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,67,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
105 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,67,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
125 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,67,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
560 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,67,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
222 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,67,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
111 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3996211

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