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苯哌辛腈 基本信息
- 中文名称：
- 苯哌辛腈
- 中文别名：
-
- 英文名称：
- 1-Piperidinebutanenitrile,a-(1-methylpropyl)-a-phenyl-, hydrochloride (1:1)
- 英文别名：
- Eurazyl;
R 154
- CAS No.：
- 53198-87-1
- 分 子 式：
- C19H28N2.ClH
- 分 子 量：
- 320.95
- 精确分子量：
- 320.20200
- PSA：
- 27.03000
- 安全术语：
- Poison by intravenous route. Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of HCl, NOx, and CN−. See also NITRILES.
- 分子结构式：
-
- SDS：
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苯哌辛腈 物化性质
- 沸点：
- 421.7ºC at 760mmHg
- 闪点：
- 174ºC
苯哌辛腈 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TM5650000
- CHEMICAL NAME :
- 1-Piperidinebutyronitrile,
alpha-sec-butyl-alpha-phenyl-, hydrochloride
- CAS REGISTRY NUMBER :
- 53198-87-1
- LAST UPDATED :
- 199506
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C19-H28-N2.Cl-H
- MOLECULAR WEIGHT :
- 320.95
- WISWESSER LINE NOTATION :
- T6NTJ A2XR&CN&Y2&1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 420 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 8,673,1958
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 700 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 49,298,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 460 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 8,673,1958
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 64 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 49,298,1960
