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氧吗啡 基本信息
- 中文名称：
- 氧吗啡
- 中文别名：
- 氧吗啡;
N-氧吗啡;
硫酸吗啡杂质A
- 英文名称：
- Morphinan-3,6-diol,7,8-didehydro-4,5-epoxy-17-methyl- (5a,6a)-, 17-oxide
- 英文别名：
- Morphine N-Oxide;
(4R,4aR,7S,7aR,12bS)-3-methyl-3-oxido-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-3-ium-7,9-diol
- CAS No.：
- 639-46-3
- 分 子 式：
- C17H19NO4
- 分 子 量：
- 301.3371
- 精确分子量：
- 301.13100
- PSA：
- 79.12000
- EINECS：
- 211-355-8
- InChI：
- The Key: AMAPEXTUMXQULJ-UHFFFAOYSA-N
- 风险术语：
- 11-23/24/25-39/23/24/25
- 分子结构式：
-
- SDS：
- 查看
氧吗啡 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QC8640000
- CHEMICAL NAME :
- Morphinan-3,6-alpha-diol,
7,8-didehydro-4,5-alpha-epoxy-17-methyl-, 17-oxide
- CAS REGISTRY NUMBER :
- 639-46-3
- LAST UPDATED :
- 199306
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C17-H19-N-O4
- MOLECULAR WEIGHT :
- 301.37
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >5300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great
Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949-
Volume(issue)/page/year: 21,668,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 820 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great
Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949-
Volume(issue)/page/year: 21,668,1969
** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 22 gm/kg/22D-I
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great
Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949-
Volume(issue)/page/year: 21,668,1969
