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匹尔屈嗪 基本信息
- 中文名称：
- 匹尔屈嗪
- 中文别名：
- 匹尔屈嗪
- 英文名称：
- 2-Propanol,1-[(6-hydrazinyl-3-pyridazinyl)methylamino]-, hydrochloride (1:2)
- 英文别名：
- Pildralazine
- CAS No.：
- 56393-22-7
- 分 子 式：
- C8H15N5O.2ClH
- 分 子 量：
- 270.20
- 精确分子量：
- 269.08100
- PSA：
- 87.30000
- 安全术语：
- Poison by intraperitoneal route. Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of NOx and HCl.
- 分子结构式：
-
- SDS：
- 查看
匹尔屈嗪 物化性质
- 密度：
- 1.302g/cm3
- 沸点：
- 486ºC at 760mmHg
- 闪点：
- 247.7ºC
匹尔屈嗪 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UR6040000
- CHEMICAL NAME :
- Pyridazine,
3-hydrazino-6-((2-hydroxypropyl)methylamino)-,
dihydrochloride
- CAS REGISTRY NUMBER :
- 56393-22-7
- LAST UPDATED :
- 199112
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C8-H15-N5-O.2Cl-H
- MOLECULAR WEIGHT :
- 270.20
- WISWESSER LINE NOTATION :
- T6NNJ CMZ F1M1YQ1 &GH 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1230 mg/kg
- TOXIC EFFECTS :
- Cardiac - pulse rate increase, without fall in BP
Vascular - BP lowering not characterized in autonomic section
- REFERENCE :
- PLRCAT Pharmacological Research Communications. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1969- Volume(issue)/page/year:
8,295,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 355 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PLRCAT Pharmacological Research Communications. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1969- Volume(issue)/page/year:
8,295,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1170 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PLRCAT Pharmacological Research Communications. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1969- Volume(issue)/page/year:
8,295,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 357 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PLRCAT Pharmacological Research Communications. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1969- Volume(issue)/page/year:
8,295,1976
