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奈立索泮 基本信息
- 中文名称：
- 奈立索泮
- 中文别名：
- 奈立索泮
- 英文名称：
- Benzenamine,4-(7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepin-1-yl)-
- 英文别名：
- 4-(7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepin-1-yl)aniline;
UNII-18Q4O339AG;
Nerisopam;
1-(4-Aminophenyl)-4-methyl-7,8-dimethoxy-5H-2,3-benzodiazepine;
5H-2,3-Benzodiazepine,1-(4-aminophenyl)-7,8-dimethoxy-4-methyl;
Nerisopam [INN];
1-(4-Aminophenyl)-7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepine
- CAS No.：
- 102771-12-0
- 分 子 式：
- C18H19N3O2
- 分 子 量：
- 0
- 精确分子量：
- 309.14800
- PSA：
- 69.20000
- 分子结构式：
-
- SDS：
- 查看
奈立索泮 物化性质
- 密度：
- 1.22g/cm3
- 沸点：
- 475.4ºC at 760mmHg
- 闪点：
- 241.3ºC
- 折射率：
- 1.612
- 蒸汽压：
- 3.34E-09mmHg at 25°C
奈立索泮 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DE8746050
- CHEMICAL NAME :
- 5H-2,3-Benzodiazepine,
1-(4-aminophenyl)-7,8-dimethoxy-4-methyl-
- CAS REGISTRY NUMBER :
- 102771-12-0
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C18-H19-N3-O2
- MOLECULAR WEIGHT :
- 309.40
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 128 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes
Lungs, Thorax, or Respiration - cyanosis
Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 39,894,1989
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 108 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes
Lungs, Thorax, or Respiration - cyanosis
Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 39,894,1989
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 275 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes
Lungs, Thorax, or Respiration - cyanosis
Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 39,894,1989
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 182 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes
Lungs, Thorax, or Respiration - cyanosis
Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 39,894,1989
