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N-乙酰氧基-2-乙酰氨基芴 基本信息
- 中文名称：
- N-乙酰氧基-2-乙酰氨基芴
- 中文别名：
-
- 英文名称：
- Acetamide,N-(acetyloxy)-N-9H-fluoren-2-yl-
- 英文别名：
- N-acetoxy-2-acetamidofluorene;
N-Acetoxy-2-fluorenylacetamide;
[acetyl(9H-fluoren-2-yl)amino] acetate;
2-Acetoxyacetylaminofluorene;
2-acetoxy-2-acetylaminofluorene;
N-Acetoxy-N-2-fluorenylacetamide;
N-Acetoxy-N-acetyl-2-aminofluorene;
N-Acetoxy-2-acetamidofluorene;
ACETOXYACETYLAMINOFLUORENE;
Acetoxyacetamidofluorene;
Acetoxy AAF;
NAAAF
- CAS No.：
- 6098-44-8
- 分 子 式：
- C17H15NO3
- 分 子 量：
- 281.33
- 精确分子量：
- 281.10500
- PSA：
- 46.61000
- InChI：
- The Key: NFOMHWALMFWNAQ-UHFFFAOYSA-N
- 安全术语：
- Questionable carcinogen with experimental tumorigenic and neoplastigenic data. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
- 分子结构式：
-
- SDS：
- 查看
N-乙酰氧基-2-乙酰氨基芴 物化性质
- 密度：
- 1.279g/cm3
- 沸点：
- 445.1ºC at 760 mmHg
- 闪点：
- 223ºC
- 折射率：
- 1.639
- 存储条件/存储方法：
- 库房通风低温干燥
N-乙酰氧基-2-乙酰氨基芴 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NC3420000
- CHEMICAL NAME :
- Hydroxylamine, N,O-diacetyl-N-fluoren-2-yl-
- CAS REGISTRY NUMBER :
- 6098-44-8
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 110
- MOLECULAR FORMULA :
- C17-H15-N-O3
- MOLECULAR WEIGHT :
- 281.33
- WISWESSER LINE NOTATION :
- L B656 HHJ ENV1&OV1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >660 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 21 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria
Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Implant
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 28 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Skin and Appendages - tumors
- TYPE OF TEST :
- Specific locus test
- TYPE OF TEST :
- Cytogenetic analysis
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TYPE OF TEST :
- Cytogenetic analysis
- TYPE OF TEST :
- DNA damage
- TYPE OF TEST :
- DNA damage
- TYPE OF TEST :
- Sister chromatid exchange
- TYPE OF TEST :
- DNA adduct
MUTATION DATA
- TYPE OF TEST :
- DNA adduct
- TEST SYSTEM :
- Mammal - species unspecified Lymphocyte
- DOSE/DURATION :
- 136 mmol/L
- REFERENCE :
- CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980-
Volume(issue)/page/year: 3,81,1982
