S-(-)-N,N-二甲基-3-羟基-3-(2-噻吩)丙胺

  • 基本信息
  • 制备方法及用途
  • 物化性质
  • 安全信息
  • MSDS
  • 上游产品
  • 下游产品

S-(-)-N,N-二甲基-3-羟基-3-(2-噻吩)丙胺 基本信息

中文名称:
S-(-)-N,N-二甲基-3-羟基-3-(2-噻吩)丙胺 
中文别名:
S-(-)-N,N-二甲基-3-羟基-3-(2-噻吩)丙胺;
(s)-(-)-N,N-二甲基-3-羟基-2-噻吩基丙胺;
(S)-(-)-N,N-二甲基-3-羟基-2-噻吩基丙胺;
(S)-(-)-3-(二甲氨基)-1-(2-噻吩基)-1-丙醇;
6 (S)-(-)-N,N-二甲基-3-羟基-3-(2-噻吩)丙胺;
(S)-3-(二甲氨基)-1-(2-噻吩基)-1-丙醇 
英文名称:
(S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine
英文别名:
(S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine;
(S)-3-(Dimethylamino)-1-(2-thienyl)-1-propanol;
(S)-(-)-N,N-dimethyl-3-hydroxy-3-(2-thienyl)propanamine;
(1S)-3-(dimethylamino)-1-thiophen-2-ylpropan-1-ol;
(S)-2-[3-(Dimethylamino)-1-hydroxypropyl]thiophene 
CAS No.:
132335-44-5
分 子 式:
C9H15NOS
分 子 量:
185.29
精确分子量:
185.08700
PSA:
51.71000
InChI:
InChI=1/C9H15NOS/c1-10(2)6-5-8(11)9-4-3-7-12-9/h3-4,7-8,11H,5-6H2,1-2H3/t8-/m0/s1
分子结构式:
SDS:
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S-(-)-N,N-二甲基-3-羟基-3-(2-噻吩)丙胺 制备方法及用途

制备方法

度洛西汀中间体。

用途简介

S-(-)-N,N-二甲基-3-羟基-3-(2-噻吩)丙胺 物化性质

密度:
1.111
熔点:
78-80ºC
沸点:
290ºC
闪点:
129ºC
折射率:
1.553
蒸汽压:
0.001mmHg at 25°C

S-(-)-N,N-二甲基-3-羟基-3-(2-噻吩)丙胺 安全信息

海关代码:
2942000000

S-(-)-N,N-二甲基-3-羟基-3-(2-噻吩)丙胺 MSDS


Section I.Chemical Product and Company Identification
    Chemical Name (S)-3-(Dimethylamino)-1-(2-thienyl)-1-propanol
    Portland OR
    Synonym        2-Thiophenemethanol, α-[2-(dimethylamino)ethyl]-, (αS)-    
    (CA INDEX NAME)
    (S)-2-[3-(Dimethylamino)-1-hydroxy-1-propyl]thiophene
    Chemical Formula        C9H15NOS    
    132335-44-5
    CAS Number

Section II.        Composition and Information on Ingredients    
    Chemical Name        CAS Number Percent (%)        TLV/PEL        Toxicology Data    
    (S)-3-(Dimethylamino)-1-(2-thienyl)-1-propanol        132335-44-5 Min. 98.0 (GC, Not available.        Not available.    
    T)

Section III. Hazards Identification
    Irritating to eyes and skin on contact. Inhalation causes irritation of the lungs and respiratory system. Inflammation of the
    Acute Health Effects
    eye is characterized by redness, watering, and itching. Skin inflammation is characterized by itching, scaling, reddening, or,
    occasionally, blistering.
    Follow safe industrial hygiene practices and always wear proper protective equipment when handling this compound.
    CARCINOGENIC EFFECTS : Not available.
    Chronic Health Effects
    MUTAGENIC EFFECTS : Not available.
    TERATOGENIC EFFECTS : Not available.
    DEVELOPMENTAL TOXICITY: Not available.
    Repeated or prolonged exposure to this compound is not known to aggravate existing medical conditions.

Section IV.        First Aid Measures    
    Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15
    Eye Contact
    minutes. Get medical attention.
    Skin Contact        In case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Wash clothing    
    before reuse. Thoroughly clean shoes before reuse. Get medical attention.
    Inhalation        If the victim is not breathing, perform mouth-to-mouth resuscitation. Loosen tight clothing such as a collar, tie, belt or    
    waistband. If breathing is difficult, oxygen can be administered. Seek medical attention if respiration problems do not
    improve.
    Ingestion        INDUCE VOMITING by sticking finger in throat. Lower the head so that the vomit will not reenter the mouth and throat.    
    Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth
    resuscitation. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible indication that the toxic
    material was ingested; the absence of such signs, however, is not conclusive.

Section V.        Fire and Explosion Data    
    Not available.
    Auto-Ignition
    Flammability        May be combustible at high temperature.    
    Flammable Limits        Not available.    
    Flash Points        Not available.    
    Combustion Products        These products are toxic carbon oxides (CO, CO2), nitrogen oxides (NO, NO2), sulfur oxides (SOx).    
    Fire Hazards
    Not available.
    Risks of explosion of the product in presence of mechanical impact: Not available.
    Explosion Hazards
    Risks of explosion of the product in presence of static discharge: Not available.
    Fire Fighting Media
    SMALL FIRE: Use DRY chemical powder.
    LARGE FIRE: Use water spray, fog or foam. DO NOT use water jet.
    and Instructions
    Consult with local fire authorities before attempting large scale fire-fighting operations.
    Continued on Next Page
    (S)-3-(Dimethylamino)-1-(2-thienyl)-1-propanol

Section VI.        Accidental Release Measures    
    Spill Cleanup        Irritating material.    
    Use a shovel to put the material into a convenient waste disposal container. Consult federal, state, and/or local authorities for
    Instructions
    assistance on disposal.

Section VII. Handling and Storage
    Handling and Storage        IRRITANT. Keep away from heat. Mechanical exhaust required. When not in use, tightly seal the container and store in a    
    dry, cool place. Avoid excessive heat and light. Do not breathe dust.
    Information
    Always store away from incompatible compounds such as oxidizing agents, acids.

Section VIII. Exposure Controls/Personal Protection
    Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended
    Engineering Controls
    exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants
    below the exposure limit.
    Splash goggles. Lab coat. Dust respirator. Boots. Gloves. Suggested protective clothing might not be sufficient; consult a
    Personal Protection
    specialist BEFORE handling this product. Be sure to use a MSHA/NIOSH approved respirator or equivalent.
    Exposure Limits        Not available.    

Section IX. Physical and Chemical Properties
    Solid. (Crystal, powder. White - almost        Solubility    
    Physical state @ 20°C        Soluble in methanol.    
    white.)
    Not available.
    Specific Gravity
    Molecular Weight        185.29        Partition Coefficient        Not available.    
    Boiling Point        Not available.        Not applicable.    
    Vapor Pressure
    Melting Point        77 to 81°C (170.6 to 177.8°F)        Vapor Density        Not available.    
    Not available.        Not available.    
    Refractive Index        Volatility    
    Critical Temperature        Not available.        Odor        Not available.    
    Not available.        Not available.    
    Viscosity        Taste    

Section X.        Stability and Reactivity Data    

This material is stable if stored under proper conditions. (See Section VII for instructions)
    Stability
    Conditions of Instability        Avoid excessive heat and light.    
    Incompatibilities        Reactive with oxidizing agents, strong acids.    

Section XI. Toxicological Information
    RTECS Number        Not available.    
    Eye Contact. Ingestion. Inhalation.
    Routes of Exposure
    Not available.
    Toxicity Data
    CARCINOGENIC EFFECTS : Not available.
    Chronic Toxic Effects
    MUTAGENIC EFFECTS : Not available.
    TERATOGENIC EFFECTS : Not available.
    DEVELOPMENTAL TOXICITY: Not available.
    Repeated or prolonged exposure to this compound is not known to aggravate existing medical conditions.
    Irritating to eyes and skin on contact. Inhalation causes irritation of the lungs and respiratory system. Inflammation of the eye
    Acute Toxic Effects
    is characterized by redness, watering, and itching. Skin inflammation is characterized by itching, scaling, reddening, or,
    occasionally, blistering.
    Follow safe industrial hygiene practices and always wear proper protective equipment when handling this compound.

Section XII.        Ecological Information    
    Ecotoxicity        Not available.    
    Environmental Fate        Not available.    
    Continued on Next Page
    (S)-3-(Dimethylamino)-1-(2-thienyl)-1-propanol

Section XIII. Disposal Considerations
    Waste Disposal        Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material with a    
    combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all
    federal, state and local regulations when disposing of the substance.

Section XIV. Transport Information
    DOT Classification        Not a DOT controlled material (United States).    
    PIN Number        Not applicable.    
    Proper Shipping Name        Not applicable.    
    Packing Group (PG)        Not applicable.    
    DOT Pictograms

Section XV. Other Regulatory Information and Pictograms
    TSCA Chemical Inventory        This product is NOT on the EPA Toxic Substances Control Act (TSCA) inventory. The following notices are required by 40    
    CFR 720.36 (C) for those products not on the inventory list:
    (EPA)
    (i) These products are supplied solely for use in research and development by or under the supervision of a technically
    qualified individual as defined in 40 CFR 720.0 et sec.
    (ii) The health risks of these products have not been fully determined. Any information that is or becomes available will be
    supplied on an MSDS sheet.
    WHMIS Classification        Not available.    
    (Canada)
    EINECS Number (EEC) 603-565-7
    EEC Risk Statements        R36/37/38- Irritating to eyes, respiratory system and skin.    


SECTION 16 - ADDITIONAL INFORMATION
N/A

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