产品供求
- 基本信息
- 物化性质
- 安全信息
- 毒理性
- 海关数据
- 上游产品
基本信息
- 中文名称：
-
- 中文别名：
-
- 英文名称：
- 4(1H)-Quinazolinone,2,3-dihydro-2-(1-naphthalenyl)-
- 英文别名：
- 2-naphthalen-1-yl-2,3-dihydro-1H-quinazolin-4-one;
2-(naphthalen-1-yl)-2,3-dihydroquinazolin-4(1h)-one;
2,3-dihydro-2-(naphthalene-1-yl)quinazolin-4(1H)-one
- CAS No.：
- 31785-60-1
- 分 子 式：
- C18H14N2O
- 分 子 量：
- 274.34
- 精确分子量：
- 274.11100
- PSA：
- 41.13000
- InChI：
- The Key: XKEIBCWTOUEGSH-UHFFFAOYSA-N
- 安全术语：
- Moderately toxic by intraperitoneal route. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
- 分子结构式：
-
- SDS：
- 查看
物化性质
- 密度：
- 1.257g/cm3
- 沸点：
- 563.6ºC at 760mmHg
- 闪点：
- 294.6ºC
- 折射率：
- 1.687
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VA3230000
- CHEMICAL NAME :
- 4(1H)-Quinazolinone, 2,3-dihydro-2-(1-naphthyl)-
- CAS REGISTRY NUMBER :
- 31785-60-1
- BEILSTEIN REFERENCE NO. :
- 0667453
- LAST UPDATED :
- 199703
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C18-H14-N2-O
- MOLECULAR WEIGHT :
- 274.34
- WISWESSER LINE NOTATION :
- T66 BVM EM DHJ D- BL66J
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 998 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NCISP* National Cancer Institute Screening Program Data Summary,
Developmental Therapeutics Program. (Bethesda, MD 20205)
Volume(issue)/page/year: JAN1986
** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg/5D-I
- TOXIC EFFECTS :
- Endocrine - changes in thymus weight
- REFERENCE :
- CCROBU Cancer Chemotherapy Reports, Part 1. (Washington, DC) V.52(6)-59,
1968-75. For publisher information, see CTRRDO. Volume(issue)/page/year:
56,163,1972
** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 480 mg/kg
- SEX/DURATION :
- male 8 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
sperm morphology, motility, and count)
Reproductive - Fertility - male fertility index (e.g. # males impregnating
females per # males exposed to fertile nonpregnant females)
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
number of implants per female; total number of implants per corpora lutea)
- REFERENCE :
- PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
(Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04-
Volume(issue)/page/year: 137,532,1971
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 400 mg/kg
- SEX/DURATION :
- male 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - testes, epididymis, sperm duct
- REFERENCE :
- PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
(Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04-
Volume(issue)/page/year: 137,532,1971
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 200 mg/kg
- SEX/DURATION :
- male 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
sperm morphology, motility, and count)
- REFERENCE :
- PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
(Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04-
Volume(issue)/page/year: 137,532,1971
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 420 mg/kg
- SEX/DURATION :
- male 21 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
sperm morphology, motility, and count)
Reproductive - Fertility - male fertility index (e.g. # males impregnating
females per # males exposed to fertile nonpregnant females)
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
number of implants per female; total number of implants per corpora lutea)
- REFERENCE :
- PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
(Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04-
Volume(issue)/page/year: 137,532,1971
海关数据
中国海关编码：2933990090
- 概述：
- 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
- 摘要/Summary：
- 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
