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氯苄沙明二氯化氢 基本信息
- 中文名称：
- 氯苄沙明二氯化氢
- 中文别名：
- 氯苄沙明二氯化氢
- 英文名称：
- Piperazine,1-[2-[(2-chlorophenyl)phenylmethoxy]ethyl]-4-[(2-methylphenyl)methyl]-,hydrochloride (1:2)
- 英文别名：
- Piperazine,1-[2-[(2-chlorophenyl)phenylmethoxy]ethyl]-4-[(2-methylphenyl)methyl]-,hydrochloride (1:2);
Chlorbenzoxamine hydrochloride;
Chlorbenzoxamine dihydrochloride;
U.C.B. 1474;
Chlorbenzoxyethamine dihydrochloride
- CAS No.：
- 5576-62-5
- 分 子 式：
- C27H31ClN2O.2ClH
- 分 子 量：
- 507.97
- 精确分子量：
- 470.18900
- PSA：
- 15.71000
- EINECS：
- 226-951-3
- InChI：
- The Key: YJNRVLPKCUSFEM-UHFFFAOYSA-N
- 安全术语：
- Poison by intravenous route. Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of NOx and Cl−.
- 分子结构式：
-
- SDS：
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氯苄沙明二氯化氢 物化性质
- 密度：
- 1.144g/cm3
- 沸点：
- 534.2ºC at 760mmHg
- 闪点：
- 276.9ºC
- 存储条件/存储方法：
- 库房低温通风干燥
氯苄沙明二氯化氢 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TL2380000
- CHEMICAL NAME :
- Piperazine,
1-(2-((o-chloro-alpha-phenylbenzyl)oxy)ethyl)-4-(o-me
thylbenzyl)-, dihydrochloride
- CAS REGISTRY NUMBER :
- 5576-62-5
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C27-H31-Cl-N2-O.2Cl-H
- MOLECULAR WEIGHT :
- 507.97
- WISWESSER LINE NOTATION :
- T6N DNTJ A2OYR&R BG& D1R B1 &GH 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3350 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 118,167,1959
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 118,167,1959
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 66 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 118,167,1959
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 118,167,1959
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 340 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - ptosis
Behavioral - somnolence (general depressed activity)
- REFERENCE :
- OSDIAF Osaka Shiritsu Daigaku Igaku Zasshi. Journal of the Osaka City
Medical Center. (Osaka, Japan) V.4-23, 1955-74. For publisher
information, see OIGZDE. Volume(issue)/page/year: 11,379,1962
