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- [5-[(二甲氨基)乙酰基]-10,11-二氢-5H-二苯并[B,F]氮杂革-3-基]氨基甲酸乙酯单盐酸盐
[5-[(二甲氨基)乙酰基]-10,11-二氢-5H-二苯并[B,F]氮杂革-3-基]氨基甲酸乙酯单盐酸盐
[5-[(二甲氨基)乙酰基]-10,11-二氢-5H-二苯并[B,F]氮杂革-3-基]氨基甲酸乙酯单盐酸盐 基本信息
- 中文名称：
- [5-[(二甲氨基)乙酰基]-10,11-二氢-5H-二苯并[B,F]氮杂革-3-基]氨基甲酸乙酯单盐酸盐
- 中文别名：
- [5-[(二甲氨基)乙酰基]-10,11-二氢-5H-二苯并[B,F]氮杂革-3-基]氨基甲酸乙酯单盐酸盐;
盐酸替拉西嗪
- 英文名称：
- Carbamic acid,N-[5-[2-(dimethylamino)acetyl]-10,11-dihydro-5H-dibenz[b,f]azepin-3-yl]-, ethylester, hydrochloride (1:1)
- 英文别名：
- Bonnecor;
Ethyl (5-((dimethylamino)acetyl)-10,11-dihydro-5H-dibenz(B,F)azepin-3-yl)carbamate monohydrochloride;
Carbamic acid,(5-((dimethylamino)acetyl)-10,11-dihydro-5H-dibenz(B,F)azepin-3-yl)-,ethyl ester,monohydrochloride;
TIRACIZINEHYDROCHLORIDE;
AWD-19-166;
Tiracizine Hydrochioride;
3-Carbethoxyamino-5-dimethylaminoacetyl-10,11-dihydrodibenz(B,F)azepine hydrochloride;
GS-015;
5H-Dibenz(B,F)azepine-3-carbamic acid,10,11-dihydro-5-((dimethylamino)acetyl)-,ethyl ester,monohydrochloride;
3-Carbethoxyamino-5-dimethylaminoacetyl-iminodibenzyle-Hydrochlorid
- CAS No.：
- 78816-67-8
- 分 子 式：
- C21H25N3O3.ClH
- 分 子 量：
- 0
- 精确分子量：
- 403.16600
- PSA：
- 61.88000
- InChI：
- The Key: XJWABFCDXKZWPV-UHFFFAOYSA-N
- 分子结构式：
-
- SDS：
- 查看
[5-[(二甲氨基)乙酰基]-10,11-二氢-5H-二苯并[B,F]氮杂革-3-基]氨基甲酸乙酯单盐酸盐 物化性质
- 沸点：
- 525.3ºC at 760 mmHg
- 闪点：
- 271.5ºC
[5-[(二甲氨基)乙酰基]-10,11-二氢-5H-二苯并[B,F]氮杂革-3-基]氨基甲酸乙酯单盐酸盐 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- HN8110000
- CHEMICAL NAME :
- 5H-Dibenz(b,f)azepine-3-carbamic acid,
10,11-dihydro-5-((dimethylamino)acetyl)-, ethyl
ester, monohydrochloride
- CAS REGISTRY NUMBER :
- 78816-67-8
- LAST UPDATED :
- 199803
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C21-H25-N3-O3.Cl-H
- MOLECULAR WEIGHT :
- 403.95
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 78 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified
Behavioral - convulsions or effect on seizure threshold
Behavioral - ataxia
- REFERENCE :
- PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18,
Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year:
40,871,1985
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10900 ug/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified
Behavioral - convulsions or effect on seizure threshold
Behavioral - ataxia
- REFERENCE :
- PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18,
Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year:
40,871,1985
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 48 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified
Behavioral - convulsions or effect on seizure threshold
Behavioral - ataxia
- REFERENCE :
- PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18,
Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year:
40,871,1985
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5400 ug/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified
Behavioral - convulsions or effect on seizure threshold
Behavioral - ataxia
- REFERENCE :
- PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18,
Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year:
40,871,1985
[5-[(二甲氨基)乙酰基]-10,11-二氢-5H-二苯并[B,F]氮杂革-3-基]氨基甲酸乙酯单盐酸盐 上游产品
