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5-甲氧基甲基-2-脱氧尿苷 基本信息
- 中文名称：
- 5-甲氧基甲基-2-脱氧尿苷
- 中文别名：
- 5-甲氧基甲基-2-脱氧尿苷
- 英文名称：
- Thymidine, a-methoxy-
- 英文别名：
- Thymidine, α-methoxy-;
1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(methoxymethyl)pyrimidine-2,4-dione;
5-Methoxymethyl-2'-deoxyuridine;
Uridine,2'-deoxy-5-methoxymethyl;
5-methoxymethyldeoxyuridine;
MMUdR;
Methoxymethyl deoxyuridine
- CAS No.：
- 5116-22-3
- 分 子 式：
- C11H16N2O6
- 分 子 量：
- 272.25
- 精确分子量：
- 272.10084
- PSA：
- 108 A2
- InChI：
- The Key: RSMISTTWWXJOOG-UEJVZZJDSA-N
- 分子结构式：
-
- SDS：
- 查看
5-甲氧基甲基-2-脱氧尿苷 物化性质
- 密度：
- 1.427±0.06 g/cm3
- 水溶解性：
- Slightly Soluble (6.3 g/L)
- 折射率：
- 1.565
5-甲氧基甲基-2-脱氧尿苷 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YU7900000
- CHEMICAL NAME :
- Uridine, 2'-deoxy-5-methoxymethyl-
- CAS REGISTRY NUMBER :
- 5116-22-3
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C11-H16-N2-O6
- MOLECULAR WEIGHT :
- 272.29
- WISWESSER LINE NOTATION :
- T6NVMVJ E1O1 A- ET5OTJ B1Q CQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - hamster
- DOSE/DURATION :
- 6 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 15 gm/kg/15D-I
- TOXIC EFFECTS :
- Liver - other changes
Blood - other changes
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - phosphatases
MUTATION DATA
- TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 256 mg/L
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
86,180,1986
