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基本信息
- 中文名称：
-
- 中文别名：
-
- 英文名称：
- 2-Pyridinamine,N-methyl-N-nitroso-
- 英文别名：
- 2-Pyridinamine, N-methyl-N-nitroso-;
N-methyl-N-pyridin-2-ylnitrous amide;
N-methyl-N-nitrosopyridin-2-amine;
2-N-nitrosomethylaminopyridine;
2-Nitrosomethylaminopyridine;
methyl-nitroso-pyridin-2-yl-amine;
N-Methyl-N-nitroso-2-aminopyridine;
N-Nitroso-N-methyl-2-aminopyridine;
Pyridine,2-nitrosomethylamino
- CAS No.：
- 16219-98-0
- 分 子 式：
- C6H7N3O
- 分 子 量：
- 137.16
- 精确分子量：
- 137.05891
- PSA：
- 45.6 A2
- InChI：
- The Key: WJDNMDMNPIKDCP-UHFFFAOYSA-N
- 安全术语：
- Poison by ingestion. Questionable carcinogen with experimental carcinogenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS.
- 分子结构式：
-
- SDS：
- 查看
物化性质
- 密度：
- 1.17±0.1 g/cm3
- 沸点：
- 286.6±22.0 °C
- 闪点：
- 127.1±22.3 °C
- 水溶解性：
- Slightly Soluble (7.7 g/L)
- 折射率：
- 1.569
- 蒸汽压：
- 0.00262mmHg at 25°C
- 蒸汽密度：
- 2.62E-3 Torr
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UT6386000
- CHEMICAL NAME :
- Pyridine, 2-nitrosomethylamino-
- CAS REGISTRY NUMBER :
- 16219-98-0
- BEILSTEIN REFERENCE NO. :
- 0118228
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C6-H7-N3-O
- MOLECULAR WEIGHT :
- 137.16
- WISWESSER LINE NOTATION :
- T6NJ BN1&NO
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 60 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - acute pulmonary edema
Gastrointestinal - ulceration or bleeding from stomach
Gastrointestinal - ulceration or bleeding from large intestine
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 250 mg/kg/50W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria
Gastrointestinal - tumors
Liver - tumors
MUTATION DATA
- TYPE OF TEST :
- Host-mediated assay
- TEST SYSTEM :
- Rodent - mouse Bacteria - Escherichia coli
- DOSE/DURATION :
- 60 mg/kg
- REFERENCE :
- CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980-
Volume(issue)/page/year: 3,415,1982
