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卡哌隆 基本信息
- 中文名称：
- 卡哌隆
- 中文别名：
- 卡哌隆
- 英文名称：
- Carbamic acid,(1-methylethyl)-, 1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidinyl ester (9CI)
- 英文别名：
- [1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] N-propan-2-ylcarbamate;
CARBAMIC ACID,ISOPROPYL-,1-(3-(p-FLUOROBENZOYL)PROPYL)PIPERID-4-YL ESTER;
Carperona [INN-Spanish];
Carperonum;
1-(3-(4-Fluorobenzoyl)propyl)-4-piperidyl N-isopropylcarbamate;
Carperonum [INN-Latin];
AL-1021;
Carperone;
(1-Methylethyl)carbamic acid,1-(4-(4-fluorophenyl)-4-oxobutyl)-4-piperidinyl ester;
1-(4-fluoro-phenyl)-4-(4-isopropylcarbamoyloxy-piperidin-1-yl)-butan-1-one;
Carperona
- CAS No.：
- 20977-50-8
- 分 子 式：
- C19H27FN2O3
- 分 子 量：
- 350.48
- 精确分子量：
- 350.20100
- PSA：
- 62.13000
- InChI：
- The Key: HJSFDYCHYVGVDC-UHFFFAOYSA-N
- 安全术语：
- Poison by ingestion and intravenous routes. Human systemic effects by ingestion: psychotropic effects. When heated to decomposition it emits very toxic F− and NOx. See also CARBAMATES.
- 分子结构式：
-
- SDS：
- 查看
卡哌隆 物化性质
- 密度：
- 1.15g/cm3
- 沸点：
- 493.7ºC at 760mmHg
- 闪点：
- 252.4ºC
- 折射率：
- 1.533
- 蒸汽压：
- 6.85E-10mmHg at 25°C
卡哌隆 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- FB3235000
- CHEMICAL NAME :
- Carbamic acid, isopropyl-,
1-(3-(p-fluorobenzoyl)propyl)piperid-4-yl ester
- CAS REGISTRY NUMBER :
- 20977-50-8
- BEILSTEIN REFERENCE NO. :
- 1551021
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C19-H27-F-N2-O3
- MOLECULAR WEIGHT :
- 350.48
- WISWESSER LINE NOTATION :
- T6NTJ A3VR DF& DOVMY1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 2140 ug/kg
- TOXIC EFFECTS :
- Behavioral - rigidity (including catalepsy)
Cardiac - change in rate
Vascular - BP lowering not characterized in autonomic section
- REFERENCE :
- CTCEA9 Current Therapeutic Research, Clinical & Experimental. (Therapeutic
Research Press, Inc., POB 514, Tenafly, NJ 07670) V.1- 1959-
Volume(issue)/page/year: 11,779,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 310 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,184,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 265 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,184,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 44 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,184,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,184,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,184,1972
卡哌隆 海关数据
中国海关编码：2933399090
- 概述：
- 2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
- 摘要/Summary：
- 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
