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匹那西泮 基本信息
- 中文名称：
- 匹那西泮
- 中文别名：
- 匹那西泮
- 英文名称：
- 2H-1,4-Benzodiazepin-2-one,7-chloro-1,3-dihydro-5-phenyl-1-(2-propyn-1-yl)-
- 英文别名：
- 7-chloro-5-phenyl-1-prop-2-ynyl-3H-1,4-benzodiazepin-2-one;
Pinazepamum [INN-Latin];
EINECS 257-934-9;
Pinazepam (INN);
7-chloro-5-phenyl-1-prop-2-ynyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one;
2H-1,4-Benzodiazepin-2-one,7-chloro-1,3-dihydro-5-phenyl-1-(2-propynyl);
7-Chlor-1,2-dihydro-1-propargyl-5-phenyl-3H-1,4-benzodiazepin-2-on;
7-chloro-2,3-dihydro-5-phenyl-1-propargyl-1H-1,4-benzodiazepine-2-one;
DEA No. 2883;
7-Chlor-2,3-dihydro-5-phenyl-1-propargyl-1H-1,4-benzodiazepin-2-on;
7-chloro-1,3-dihydro-1(2-propynyl)-2H-1,4-benzodiazepin-2-one;
ZAMI 905;
Pinazepam
- CAS No.：
- 52463-83-9
- 分 子 式：
- C18H13ClN2O
- 分 子 量：
- 308.78
- 精确分子量：
- 308.07200
- PSA：
- 32.67000
- InChI：
- The Key: MFZOSKPPVCIFMT-UHFFFAOYSA-N
- 安全术语：
- Poison by intraperitoneal route. Moderately toxic by ingestion. Used as an antidepressant. Note: This is a controlled substance (depressant) listed in the U.S. Code of Federal Regulations, Title 21 Part 1308.14 (1985). When heated to decomposition it emits toxic fumes of Cl− and NOx.
- 分子结构式：
-
- SDS：
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匹那西泮 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DF2375000
- CHEMICAL NAME :
- 2H-1,4-Benzodiazepin-2-one,
1,3-dihydro-7-chloro-5-phenyl-1-(2-propynyl)-
- CAS REGISTRY NUMBER :
- 52463-83-9
- BEILSTEIN REFERENCE NO. :
- 0758533
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C18-H13-Cl-N2-O
- MOLECULAR WEIGHT :
- 308.78
- WISWESSER LINE NOTATION :
- T67 GNV JN IHJ CG G2UU1 JR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5819 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 25,934,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 622 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 25,934,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1302 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- USXXAM United States Patent Document. (U.S. Patent Office, Box 9,
Washington, DC 20231) Volume(issue)/page/year: #4313943
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 266 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 25,934,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 494 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 25,934,1975
