诺米芬辛

  • 基本信息
  • 物化性质
  • 安全信息
  • 毒理性
  • 海关数据
  • 上游产品
  • 下游产品

诺米芬辛 基本信息

中文名称:
诺米芬辛 
中文别名:
诺米芬辛;
苯异喹胺;
2-甲基-4-苯基-8-氨基-1,2,3,4-四氢异喹啉 
英文名称:
8-Isoquinolinamine,1,2,3,4-tetrahydro-2-methyl-4-phenyl-
英文别名:
nomifensine;
2-Methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine;
Nomifenison;
1,2,3,4-tetrahydro-8-amino-2-methyl-4-phenyl-isoquinolin;
8-Amino-1,2,3,4-tetrahydro-2-methyl-4-phenylisoquinoline;
linamiphen;
Nomifensine Maleate;
8-Isoquinolinamine,1,2,3,4-tetrahydro-2-methyl-4-phenyl;
8-amino-4-phenyl-2-methyl-1,2,3,4-tetrahydro-isoquinoline;
Nomifensine;
8-Amino-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline;
Nomifensin;
1,2,3,4-tetrahydro-2-methyl-4-phenyl-8-isoquinolinamin;
1,2,3,4-tetrahydro-2-methyl-4-phenyl-8-isoquinolinamine 
CAS No.:
24526-64-5
分 子 式:
C16H18N2
分 子 量:
238.32800
精确分子量:
238.14700
PSA:
29.26000
InChI:
The Key: XXPANQJNYNUNES-UHFFFAOYSA-N
分子结构式:
SDS:
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诺米芬辛 物化性质

密度:
1.114g/cm3
沸点:
378.4ºC at 760mmHg
闪点:
164ºC
折射率:
1.622
蒸汽压:
6.28E-06mmHg at 25°C

诺米芬辛 安全信息

包装等级:
III
风险类别:
6.1(b)
海关代码:
2933499090
危险类别码:
22-36/37/38
危险标志:
Xn: Harmful;

诺米芬辛 毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NX4912700
CHEMICAL NAME :
Isoquinoline, 1,2,3,4-tetrahydro-8-amino-2-methyl-4-phenyl-
CAS REGISTRY NUMBER :
24526-64-5
LAST UPDATED :
199512
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C16-H18-N2
MOLECULAR WEIGHT :
238.36
WISWESSER LINE NOTATION :
T66 CNT&J C1 ER& JZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - woman
DOSE/DURATION :
7 mg/kg/7D-I
TOXIC EFFECTS :
Blood - hemorrhage Blood - thrombocytopenia
REFERENCE :
BMJOAE British Medical Journal. (British Medical Assoc., BMA House, Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year: 288,830,1984
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - woman
DOSE/DURATION :
500 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
HUTODJ Human Toxicology. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants., RG 21 2XS, UK) V.1- 1981- Volume(issue)/page/year: 6,247,1987
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
260 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay) Behavioral - aggression
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 32,873,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
128 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JNPHAG Journal de Pharmacologie. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1970- Volume(issue)/page/year: 17,37,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
264 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes
REFERENCE :
DRUGAY Drugs. International Journal of Current Therapeutics and Applied Pharmacology Reviews. (ADIS Press International Inc., Suite B-30, Oxford Ct. Business Center, 582 Middletown Blvd., Langhorne, PA 19047) V.1- 1971- Volume(issue)/page/year: 18,1,1979 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
4 mg/kg
SEX/DURATION :
lactating female 1 day(s) post-birth
TOXIC EFFECTS :
Reproductive - Maternal Effects - other effects
REFERENCE :
GOBIDS Gynecologic and Obstetric Investigation. (S. Karger Pub., Inc., 79 Fifth Ave., New York, NY 10003) V.9- 1978- Volume(issue)/page/year: 23,103,1987

诺米芬辛 海关数据

中国海关编码:2933499090

概述:
2933499090. 其他含喹琳或异喹啉环系的化合物〔但未进一步稠合的〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素:
品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
摘要/Summary:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

诺米芬辛 下游产品

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中山福韵生物科技有限公司

产品介绍:
产品名称:诺米芬辛 Cas号:24526-64-5 纯度: 包装信息:洽谈 价格:洽谈
联系方式:
联系人:刘 电话:0760-85330351 手机:18666170015