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杆孢菌素 E 基本信息
- 中文名称：
- 杆孢菌素 E
- 中文别名：
-
- 英文名称：
- Verrucarin A,2',3'-didehydro-7'-deoxo-2'-deoxy-7'-[(1R)-1-hydroxyethyl]-, (2'E,7'R)-
- 英文别名：
- RORIDIN E;
Verrucarin A,2',3'-didehydro-7'-deoxo-2'-deoxy-7'-(1-hydroxyethyl)-,(2'E,7'R(R));
Verrucarin A,2',3'-didehydro-7'-deoxo-2'-deoxy-7'-((1R)-1-hydroxyethyl)-,(2'E,7'R);
roridinee;
(2'E,7'R)-2',3'-Didehydro-7'-deoxo-2'-deoxy-7'-[(R)-1-hydroxyethyl]verrucarin A
- CAS No.：
- 16891-85-3
- 分 子 式：
- C29H38O8
- 分 子 量：
- 514.61
- 精确分子量：
- 514.25700
- PSA：
- 103.82000
- InChI：
- The Key: KEEQQEKLEZRLDS-JPEFJRGDSA-N
- 分子结构式：
-
- SDS：
- 查看
杆孢菌素 E 物化性质
- 密度：
- 1.26g/cm3
- 沸点：
- 740.3ºC at 760 mmHg
- 闪点：
- 243.4ºC
- 折射率：
- 1.58
- 蒸汽压：
- 2.67E-25mmHg at 25°C
杆孢菌素 E 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YX9821500
- CHEMICAL NAME :
- Verrucarin A,
2',3'-didehydro-7'-deoxo-2'-deoxy-7'-(1-hydroxyethyl)
-, (2'E,7'R(R))-
- CAS REGISTRY NUMBER :
- 16891-85-3
- LAST UPDATED :
- 198611
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C29-H38-O8
- MOLECULAR WEIGHT :
- 514.67
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 55 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
Behavioral - muscle contraction or spasticity
- REFERENCE :
- TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,
UK) V.1- 1962- Volume(issue)/page/year: 23,731,1985
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
Behavioral - muscle contraction or spasticity
- REFERENCE :
- TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,
UK) V.1- 1962- Volume(issue)/page/year: 23,731,1985
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 17300 ug/kg
- TOXIC EFFECTS :
- Gastrointestinal - ulceration or bleeding from large intestine
Gastrointestinal - hypermotility, diarrhea
- REFERENCE :
- TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,
UK) V.1- 1962- Volume(issue)/page/year: 23,731,1985
