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氯苯那敏盐酸盐 基本信息
- 中文名称：
- 氯苯那敏盐酸盐
- 中文别名：
-
- 英文名称：
- Ethanamine,2-[1-(4-chlorophenyl)-1-phenylethoxy]-N,N-dimethyl-, hydrochloride (1:1)
- 英文别名：
- 2-[1-(4-chlorophenyl)-1-phenylethoxy]-N,N-dimethylethanamine,hydrochloride;
Systral;
EINECS 209-227-1;
Chlorphenoxamine HCl;
{2-[1-(4-chloro-phenyl)-1-phenyl-ethoxy]-ethyl}-dimethyl-amine,hydrochloride;
chlophenoxamine hydrochloride;
Phenoxene;
chlorophenoxamine hydrochloride;
Contristamine,hydrochloride;
2-[1-(4-chlorophenyl)-1-phenyl-ethoxy]-N,N-dimethylethanamine hydrochloride;
Chlorphenoxamine hydrochloride;
Substanz NR. 1766 [German];
{2-[1-(4-Chlor-phenyl)-1-phenyl-aethoxy]-aethyl}-dimethyl-amin,Hydrochlorid;
Phenoxene hydrochloride
- CAS No.：
- 562-09-4
- 分 子 式：
- C18H22ClNO.ClH
- 分 子 量：
- 340.32
- 精确分子量：
- 339.11600
- PSA：
- 12.47000
- EINECS：
- 209-227-1
- InChI：
- The Key: PAQUKACYLLABHB-UHFFFAOYSA-N
- 安全术语：
- Poison by ingestion and subcutaneous routes. Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of Cl− and NOx.
- 分子结构式：
-
- SDS：
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氯苯那敏盐酸盐 物化性质
- 沸点：
- 383.7ºC at 760 mmHg
- 闪点：
- 185.9ºC
氯苯那敏盐酸盐 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KR2975000
- CHEMICAL NAME :
- Ethylamine,
2-((p-chloro-alpha-methyl-alpha-phenylbenzyl)oxy)-N,N
-dimethyl-, hydrochloride
- CAS REGISTRY NUMBER :
- 562-09-4
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C18-H22-Cl-N-O.Cl-H
- MOLECULAR WEIGHT :
- 340.32
- WISWESSER LINE NOTATION :
- GR DX1&R&O2N1&1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland,
OH, Chemical Rubber Co., 1969 Volume(issue)/page/year: -,31,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 345 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 4,262,1954
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 161 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
2,83,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 159 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 4,262,1954
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 44 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 4,262,1954
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 30800 ug/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
4,638,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 220 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 4,189,1954
