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普拉马林 基本信息
- 中文名称：
- 普拉马林
- 中文别名：
-
- 英文名称：
- Ajmalanium,17,21-dihydroxy-4-propyl-, (17R,21a)-
- 英文别名：
- Prajmaline;
N-n-Propyl-21-epi-isoajmalinium Kation;
Prajmalium;
N-Propylajmaline;
N-Propyl-ajmalinium
- CAS No.：
- 35080-11-6
- 分 子 式：
- C23H33N2O2
- 分 子 量：
- 369.58
- 精确分子量：
- 369.25400
- PSA：
- 43.70000
- InChI：
- The Key: UAUHEPXILIZYCU-HUJQOCOMSA-N
- 安全术语：
- Poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of NOx. See also other ajmalines.
- 分子结构式：
-
- SDS：
- 查看
普拉马林 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AX8155800
- CHEMICAL NAME :
- Ajmalanium, 17,21-dihydroxy-4-propyl-,
(17R,21-alpha)-
- CAS REGISTRY NUMBER :
- 35080-11-6
- LAST UPDATED :
- 198602
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C23-H33-N2-O2
- MOLECULAR WEIGHT :
- 369.58
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1400 ug/kg
- TOXIC EFFECTS :
- Cardiac - other changes
- REFERENCE :
- PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18,
Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year:
31,36,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 65500 ug/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex)
Behavioral - convulsions or effect on seizure threshold
Behavioral - ataxia
- REFERENCE :
- CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA,
1255 Howard St., San Francisco, CA 94103) V.6- 1958-
Volume(issue)/page/year: 22,2329,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3400 ug/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex)
Behavioral - convulsions or effect on seizure threshold
Behavioral - ataxia
- REFERENCE :
- CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA,
1255 Howard St., San Francisco, CA 94103) V.6- 1958-
Volume(issue)/page/year: 22,2329,1974
