(Z)-1,2-二乙基二氮杂烯

  • 基本信息
  • 毒理性
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(Z)-1,2-二乙基二氮杂烯 基本信息

中文名称:
(Z)-1,2-二乙基二氮杂烯 
中文别名:
(Z)-1,2-二乙基二氮杂烯 
英文名称:
Diazene, 1,2-diethyl-
英文别名:
diethyldiazene;
Azobisethane;
ETHANE,AZO;
Diaethyl-diazen;
AZOETHANE 
CAS No.:
821-14-7
分 子 式:
C4H10N2
分 子 量:
86.16
精确分子量:
86.08440
PSA:
24.72000
InChI:
The Key: RYWVIDHZGXHFNG-UHFFFAOYSA-N
安全术语:
Moderate acute toxicity. An experimental teratogen. Questionable carcinogen with experimental carcinogenic and tumorigenic data. When heated to decomposition it emits toxic fumes of NOx. An unstable, dangerously explosive material in concentrated state.
分子结构式:
SDS:
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(Z)-1,2-二乙基二氮杂烯 毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KH4025000
CHEMICAL NAME :
Ethane, azo-
CAS REGISTRY NUMBER :
821-14-7
BEILSTEIN REFERENCE NO. :
1736139
LAST UPDATED :
199612
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C4-H10-N2
MOLECULAR WEIGHT :
86.16
WISWESSER LINE NOTATION :
2NUN2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ZEKBAI Zeitschrift fuer Krebsforschung. (Berlin, Fed. Rep. Ger.) V.1-75, 1903-71. For publisher information, see JCROD7. Volume(issue)/page/year: 67,31,1965 ** TUMORIGENIC DATA **
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
37 mg/kg/1H female 22 day(s) after conception
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Reproductive - Tumorigenic effects - transplacental tumorigenesis Brain and Coverings - tumors
REFERENCE :
IARCCD IARC Scientific Publications. (Geneva, Switzerland) No.1-26, 1971-78. For publisher information, see IAPUDO. Volume(issue)/page/year: 4,45,1973
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1250 mg/kg/26W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Blood - leukemia
REFERENCE :
ZEKBAI Zeitschrift fuer Krebsforschung. (Berlin, Fed. Rep. Ger.) V.1-75, 1903-71. For publisher information, see JCROD7. Volume(issue)/page/year: 67,31,1965
TYPE OF TEST :
TC - Toxic concentration (other than lowest)
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4000 ppm/1H female 15 day(s) after conception
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Reproductive - Tumorigenic effects - transplacental tumorigenesis Brain and Coverings - tumors
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 6,584,1968
TYPE OF TEST :
TC - Toxic concentration (other than lowest)
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
300 mg/kg/1H female 15 day(s) after conception
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Reproductive - Tumorigenic effects - transplacental tumorigenesis Brain and Coverings - tumors
REFERENCE :
EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945- Volume(issue)/page/year: 24,561,1968 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
DOSE :
1250 mg/kg/1H
SEX/DURATION :
female 15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
IARCCD IARC Scientific Publications. (Geneva, Switzerland) No.1-26, 1971-78. For publisher information, see IAPUDO. Volume(issue)/page/year: 4,45,1973

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