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- 4-氯-2'-[(甲基氨基)甲基]二苯甲醇盐酸盐
4-氯-2'-[(甲基氨基)甲基]二苯甲醇盐酸盐 基本信息
- 中文名称：
- 4-氯-2'-[(甲基氨基)甲基]二苯甲醇盐酸盐
- 中文别名：
- 4-Chloro-2'-[(methylamino)methyl]benzhydrol hydrochloride
- 英文名称：
- Benzenemethanol, a-(4-chlorophenyl)-2-[(methylamino)methyl]-,hydrochloride (9CI)
- 英文别名：
- 4-Chloro-2'-[(methylamino)methyl]benzhydrol hydrochloride;
Benzhydrol,4'-chloro-2-[(methylamino)methyl]-,hydrochloride;
PR-F-36Cl;
PR-F-36-C1;
Setazindol hydrochloride;
F-36
- CAS No.：
- 27683-73-4
- 分 子 式：
- C15H16ClNO.ClH
- 分 子 量：
- 298.23
- 精确分子量：
- 297.06900
- PSA：
- 32.26000
- InChI：
- The Key: JOKHHLKHNMKCON-UHFFFAOYSA-N
- 安全术语：
- Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx and Cl−.
- 分子结构式：
-
- SDS：
- 查看
4-氯-2'-[(甲基氨基)甲基]二苯甲醇盐酸盐 物化性质
- 沸点：
- 396ºC at 760 mmHg
- 闪点：
- 193.3ºC
- 蒸汽压：
- 5.54E-07mmHg at 25°C
- 存储条件/存储方法：
- 库房低温,通风,干燥,与食品原料分开存放
4-氯-2'-[(甲基氨基)甲基]二苯甲醇盐酸盐 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DC7606500
- CHEMICAL NAME :
- Benzhydrol, 4'-chloro-2-((methylamino)methyl)-,
hydrochloride
- CAS REGISTRY NUMBER :
- 27683-73-4
- LAST UPDATED :
- 199412
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C15-H16-Cl-N-O.Cl-H
- MOLECULAR WEIGHT :
- 298.23
- WISWESSER LINE NOTATION :
- GR DYQR B1M1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 560 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor
Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 211,253,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 115 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor
Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 211,253,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 328 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor
Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 211,253,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 230 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor
Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 211,253,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 54 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor
Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 211,253,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 83 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor
Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 211,253,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 53 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor
Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 211,253,1974
** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 112 gm/kg/8W-C
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 35,240,1985
