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紫霉素 基本信息
- 中文名称：
- 紫霉素
- 中文别名：
- 紫霉素;
紫黴素
- 英文名称：
- Glycine,3-amino-N-[(3S)-3,6-diamino-1-oxohexyl]-L-alanyl-L-seryl-L-seryl-(2Z)-3-[(aminocarbonyl)amino]-2,3-didehydroalanyl-2-[(4R,6S)-2-amino-1,4,5,6-tetrahydro-6-hydroxy-4-pyrimidinyl]-,(5®13)-lactam, (2S)-
- 英文别名：
- viomycin;
Tuberactomycin B;
Viomicina;
Tuberactinomycin B;
VIOMYCIN;
Florimycin;
(3S)-3,6-diamino-N-[(3S,6Z,9S,12S,15S)-3-[(4S,6R)-2-amino-4-hydroxy-1,4,5,6-tetrahydropyrimidin-6-yl]-6-[(carbamoylamino)methylidene]-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-1,4,7,10,13-pentazacyclohexadec-15-yl]hexanamide;
Celiomycin;
Viomycinum;
Viomycine
- CAS No.：
- 32988-50-4
- 分 子 式：
- C25H43N13O10
- 分 子 量：
- 685.81
- 精确分子量：
- 685.32600
- PSA：
- 392.86000
- EINECS：
- 251-323-0
- InChI：
- The Key: GXFAIFRPOKBQRV-GHXCTMGLSA-N
- 安全术语：
- Poison by intravenous route. Moderately toxic by ingestion, intraperitoneal, intramuscular and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. Used as an antibiotic. When heated to decomposition it emits toxic fumes of NOx.
- 分子结构式：
-
- SDS：
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紫霉素 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- ZA3900000
- CHEMICAL NAME :
- Viomycin
- CAS REGISTRY NUMBER :
- 32988-50-4
- LAST UPDATED :
- 199609
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C25-H43-N13-O10
- MOLECULAR WEIGHT :
- 685.81
- WISWESSER LINE NOTATION :
- T-16-MVYMV GMV JMV NMVTJ CU1MVZ F1Q I1Q LMV1YZ3Z P-
DT6MYMTJ BUM FQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1075 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
GKNT, 1982 Volume(issue)/page/year: -,69,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1750 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
GKNT, 1982 Volume(issue)/page/year: -,69,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1637 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
GKNT, 1982 Volume(issue)/page/year: -,69,1982
** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 7 gm/kg
- SEX/DURATION :
- female 6-10 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
before birth)
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
Reproductive - Effects on Embryo or Fetus - fetal death
- REFERENCE :
- OSDIAF Osaka Shiritsu Daigaku Igaku Zasshi. Journal of the Osaka City
Medical Center. (Osaka, Japan) V.4-23, 1955-74. For publisher
information, see OIGZDE. Volume(issue)/page/year: 14,107,1965
