• 基本信息
  • 物化性质
  • 毒理性

基本信息

中文名称:
 
中文别名:
N,N-diethyl-2-[2-(2-methyl-5-phenylpyrrol-1-yl)phenoxy]ethanamine,hydrochloride 
英文名称:
Ethanamine,N,N-diethyl-2-[2-(2-methyl-5-phenyl-1H-pyrrol-1-yl)phenoxy]-, hydrochloride(1:1)
英文别名:
N,N-diethyl-2-[2-(2-methyl-5-phenylpyrrol-1-yl)phenoxy]ethanamine,hydrochloride;
1-[2-(2-Diaethylamino-aethoxy)-phenyl]-2-methyl-5-phenyl-pyrrol;
1-(2-<2-Diethylamino-ethoxy>-phenyl)-2-methyl-5-phenyl-pyrrol;
Leiopyrrole;
Pyrrole,1-(o-(2-(diethylamino)ethoxy)phenyl)-2-methyl-5-phenyl;
Leiopirrol [INN-Spanish];
Ethanamine,N,N-diethyl-2-(2-(2-methyl-5-phenyl-1H-pyrrol-1-yl)phenoxy);
Leiopirrol;
1-[2-(2-Diaethylamino-aethoxy)-phenyl]-2-methyl-5-phenyl-pyrrol,Hydrochlorid;
1-[2-(2-diethylamino-ethoxy)-phenyl]-2-methyl-5-phenyl-pyrrole,hydrochloride;
Leiopyrrolum [INN-Latin];
1-(o-(2-(Diethylamino)ethoxy)phenyl)-2-methyl-5-phenylpyrrole;
2-Methyl-5-phenyl-1-<2-(2-diethylamino-ethoxy)-phenyl>-pyrrol;
1-[2-(2-diethylamino-ethoxy)-phenyl]-2-methyl-5-phenyl-pyrrole;
DV 714;
Leioplegil 
CAS No.:
14435-78-0
分 子 式:
C23H28N2O.ClH
分 子 量:
348.4812
精确分子量:
384.19700
PSA:
17.40000
InChI:
The Key: JTOGCNWNXIHUHX-UHFFFAOYSA-N
分子结构式:
SDS:
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物化性质

密度:
1.01g/cm3
沸点:
497.9ºC at 760mmHg
闪点:
254.9ºC

毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UX9465070
CHEMICAL NAME :
Pyrrole, 1-(o-(2-(diethylamino)ethoxy)phenyl)-2-methyl-5-pheny l-, monohydrochloride
CAS REGISTRY NUMBER :
14435-78-0
LAST UPDATED :
199603
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C23-H28-N2-O.Cl-H
MOLECULAR WEIGHT :
384.99

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 17,287,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
185 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 17,287,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
475 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 17,287,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
115 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 19,753,1961
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
28 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 17,287,1962

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