N-(3-氯丙基)-alpha-甲基苯乙胺盐酸盐

  • 基本信息
  • 物化性质
  • 毒理性

N-(3-氯丙基)-alpha-甲基苯乙胺盐酸盐 基本信息

中文名称:
N-(3-氯丙基)-alpha-甲基苯乙胺盐酸盐 
中文别名:
N-(3-氯丙基)-alpha-甲基苯乙胺盐酸盐 
英文名称:
Benzeneethanamine,N-(3-chloropropyl)-a-methyl-, hydrochloride (1:1)
英文别名:
N-(3-chloropropyl)-1-phenylpropan-2-amine,hydrochloride;
Mefenorex HCl;
Doracil;
Pondinil;
EINECS 226-985-9;
Rondimen;
Ro 4-5282;
N-Chloropropylamphetamine hydrochloride;
R 4-5282;
Mefenorex hydrochloride 
CAS No.:
5586-87-8
分 子 式:
C12H18ClN.ClH
分 子 量:
248.22
精确分子量:
247.08900
PSA:
12.03000
EINECS:
226-985-9
安全术语:
Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. When heated to decomposition it emits very toxic fumes of NOx and Cl−.
分子结构式:
SDS:
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N-(3-氯丙基)-alpha-甲基苯乙胺盐酸盐 物化性质

沸点:
305.1ºC at 760mmHg
闪点:
138.3ºC

N-(3-氯丙基)-alpha-甲基苯乙胺盐酸盐 毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SH2100000
CHEMICAL NAME :
Phenethylamine, N-(3-chloropropyl)-alpha-methyl-, hydrochloride
CAS REGISTRY NUMBER :
5586-87-8
LAST UPDATED :
199512
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C12-H18-Cl-N.Cl-H
MOLECULAR WEIGHT :
248.22
WISWESSER LINE NOTATION :
G3MY1&1R &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
410 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 19,748,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
35 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 19,748,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
230 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 19,748,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
144 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,356,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 19,748,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
49 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,356,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
236 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,356,1972

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