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二(氯甲基)-苯 基本信息
- 中文名称：
- 二(氯甲基)-苯
- 中文别名：
-
- 英文名称：
- Benzene,bis(chloromethyl)-
- 英文别名：
- bis(chloromethyl)benzene;
Xylylene dichloride.
- CAS No.：
- 28347-13-9
- 分 子 式：
- C8H8Cl2
- 分 子 量：
- 175.06
- 精确分子量：
- 870.00200
- PSA：
- 0.00000
- EINECS：
- 248-982-1
- 安全术语：
- Poison by inhalation. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of Cl−. See CHLORINATED HYDROCARBONS, AROMATIC.
- 分子结构式：
-
- SDS：
- 查看
二(氯甲基)-苯 物化性质
- 密度：
- 1.208 g/cm3
- 沸点：
- 239.5ºC at 760 mmHg
- 闪点：
- 114.1ºC
- 折射率：
- 1.544
- 蒸汽压：
- 0.0618mmHg at 25°C
二(氯甲基)-苯 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- ZE4055000
- CHEMICAL NAME :
- Xylene, alpha,alpha'-dichloro-
- CAS REGISTRY NUMBER :
- 28347-13-9
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C8-H8-Cl2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
GKNT, 1982 Volume(issue)/page/year: -,26,1982
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 200 mg/m3/4H
- TOXIC EFFECTS :
- Behavioral - excitement
Behavioral - ataxia
Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/page/year: 10(9),36,1966
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 467 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor
Behavioral - muscle weakness
Lungs, Thorax, or Respiration - respiratory stimulation
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/page/year: 10(9),36,1966
- TYPE OF TEST :
- LC75 - Lethal Concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 75 mg/m3/2H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
GKNT, 1982 Volume(issue)/page/year: -,26,1982
** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4312 mg/kg/6W-I
- TOXIC EFFECTS :
- Related to Chronic Data - death
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/page/year: 10(9),36,1966
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1500 ug/m3/4H/3W-I
- TOXIC EFFECTS :
- Cardiac - other changes
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - cytochrome oxidases (including oxidative phosphorylation)
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - dehydrogenases
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/page/year: 10(9),36,1966
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-RUSSIA:STEL 1 mg/m3 JAN 1993
