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普立地芬 基本信息
- 中文名称：
- 普立地芬
- 中文别名：
- 普立地芬
- 英文名称：
- Pyrrolidine,3-(diphenylmethylene)-1-ethyl-, hydrochloride (1:1)
- 英文别名：
- 3-benzhydrylidene-1-ethylpyrrolidine,hydrochloride;
Pridefine hydrochloride (USAN);
PRIDEFINE HYDROCHLORIDE;
AHR-1118;
1-Ethyl-3-diphenylmethylenepyrrolidine hydrochloride;
Pridefine;
Pridefine HCl;
3-(Diphenylmethylene)-1-ethylpyrrolidine hydrochloride
- CAS No.：
- 23239-78-3
- 分 子 式：
- C19H21N.ClH
- 分 子 量：
- 0
- 精确分子量：
- 299.14400
- PSA：
- 3.24000
- 分子结构式：
-
- SDS：
- 查看
普立地芬 物化性质
- 沸点：
- 396.1ºC at 760mmHg
- 闪点：
- 173ºC
- 蒸汽压：
- 1.75E-06mmHg at 25°C
普立地芬 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UY1050000
- CHEMICAL NAME :
- Pyrrolidine, 3-diphenylmethylene-1-ethyl-,
hydrochloride
- CAS REGISTRY NUMBER :
- 23239-78-3
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C19-H21-N.Cl-H
- MOLECULAR WEIGHT :
- 299.87
- WISWESSER LINE NOTATION :
- T5N CYTJ A2 CUYR&R &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 166 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,199,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 90 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,199,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 39 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,199,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 144 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,199,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 167 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,199,1972
