4-甲氧基-N'-(吡啶-3-基甲基)苯-1,3-二甲酰胺

  • 基本信息
  • 物化性质
  • 毒理性

4-甲氧基-N'-(吡啶-3-基甲基)苯-1,3-二甲酰胺 基本信息

中文名称:
4-甲氧基-N'-(吡啶-3-基甲基)苯-1,3-二甲酰胺 
中文别名:
 
英文名称:
1,3-Benzenedicarboxamide,4-methoxy-N3-(3-pyridinylmethyl)-
英文别名:
4-methoxy-3-N-(pyridin-3-ylmethyl)benzene-1,3-dicarboxamide;
3-Carbamyl-(3'-picolyl)-4-methoxy-1-benzamide;
4-Methoxy-N(sup 3)-(3-pyridinylmethyl)-1,3-benzenedicarboxamide;
4-methoxy-N3-(pyridin-3-ylmethyl)benzene-1,3-dicarboxamide;
1,3-Benzenedicarboxamide,4-methoxy-N3-(3-pyridinylmethyl);
G 619;
1,3-Benzenedicarboxamide,4-methoxy-N(sup 3)-(3-pyridinylmethyl) 
CAS No.:
108828-56-4
分 子 式:
C15H15N3O3
分 子 量:
0
精确分子量:
285.11100
PSA:
98.79000
分子结构式:
SDS:
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4-甲氧基-N'-(吡啶-3-基甲基)苯-1,3-二甲酰胺 物化性质

密度:
1.26g/cm3
沸点:
537.9ºC at 760mmHg
闪点:
279.1ºC
折射率:
1.605
蒸汽压:
1.21E-11mmHg at 25°C

4-甲氧基-N'-(吡啶-3-基甲基)苯-1,3-二甲酰胺 毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CZ2268500
CHEMICAL NAME :
1,3-Benzenedicarboxamide, 4-methoxy-N(sup 3)-(3-pyridinylmethyl)-
CAS REGISTRY NUMBER :
108828-56-4
LAST UPDATED :
199512
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C15-H15-N3-O3
MOLECULAR WEIGHT :
285.33

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1725 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Behavioral - ataxia Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
CDREEA Cardiovascular Drug Reviews. (Raven Press, 1185 Avenue of the Americas, New York, NY 10036) V.6- 1988- Volume(issue)/page/year: 11,116,1993
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1326 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Behavioral - ataxia Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
CDREEA Cardiovascular Drug Reviews. (Raven Press, 1185 Avenue of the Americas, New York, NY 10036) V.6- 1988- Volume(issue)/page/year: 11,116,1993
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
569 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Behavioral - ataxia Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
CDREEA Cardiovascular Drug Reviews. (Raven Press, 1185 Avenue of the Americas, New York, NY 10036) V.6- 1988- Volume(issue)/page/year: 11,116,1993
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1758 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Behavioral - ataxia Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
CDREEA Cardiovascular Drug Reviews. (Raven Press, 1185 Avenue of the Americas, New York, NY 10036) V.6- 1988- Volume(issue)/page/year: 11,116,1993
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
966 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Behavioral - ataxia Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
CDREEA Cardiovascular Drug Reviews. (Raven Press, 1185 Avenue of the Americas, New York, NY 10036) V.6- 1988- Volume(issue)/page/year: 11,116,1993
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
463 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Behavioral - ataxia Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
CDREEA Cardiovascular Drug Reviews. (Raven Press, 1185 Avenue of the Americas, New York, NY 10036) V.6- 1988- Volume(issue)/page/year: 11,116,1993

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