去甲氧基醉椒素

外观与性状：

白色至淡的黄色粉末

密度：

1.18 g/cm3

熔点：

138-140ºC

沸点：

440ºC at 760 mmHg

闪点：

188ºC

折射率：

1.588

蒸汽压：

6.09E-08mmHg at 25°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :

UQ1240000

CHEMICAL NAME :

2H-Pyran-2-one, 4-methoxy-6-styryl-, (E)-

CAS REGISTRY NUMBER :

15345-89-8

LAST UPDATED :

199206

DATA ITEMS CITED :

3

MOLECULAR FORMULA :

C14-H12-O3

MOLECULAR WEIGHT :

228.26

WISWESSER LINE NOTATION :

T6OVJ DO1 F1U1R DO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

>800 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 177,261,1969

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

>800 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 177,261,1969

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

55 mg/kg

TOXIC EFFECTS :

Behavioral - anticonvulsant

REFERENCE :

AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 177,261,1969